Protein Purification
Selleck Chemical LLC Baicalin 10mg 21967-41-9
Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Tadalafil 50mg 171596-29-5 IC351
Tadalafil (IC351) is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay. Tadalafil is at least 9000 times more selective for PDE5 than most of the other families of PDEs, with the exception of PDE11. It can partial inhibits PDE11 *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Bortezomib (PS-341) 100mg 179324-69-7 LDP-341, MLM341
Bortezomib (PS-341, LDP-341, MLM341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-?B and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Research Products International Corp Protease Inhibitor Cocktail VII, His-Tag Sequences, 1 Vial
Mixture of five protease inhibitors for purification of proteins containing hexa histidine tagged sequences. Supplied in 1ml DMSO. Will inhibit proteases extracted from 10g of cells.
Contains:
Bestatin
E-64
Pepstatin A
Phosphoromidon
Specificity:
Cysteine Proteases
Aspartic Proteases
Aminopeptidoses and Metalloproteases
Cayman Chemical LSD1 InhIbItr Screeng as 96Wel
LSD1 is a histone demethylase whose actions on specific lysine residues alter transcription of chromosomal DNA. It also inhibits the tumor suppressor activity of p53 by demethylating a specific lysine residue. Inhibitors of LSD1 are important tools used to elucidate mechanisms of transcription and cell cycle progression and have therapeutic potential for treating cancer. Cayman’s LSD1 Inhibitor Screening Assay provides a convenient fluorescence-based method for screening LSD1-specific inhibitors. The assay is based on the multistep enzymatic reaction in which LSD1 first produces H2O2 during the demethylation of lysine 4 on a peptide corresponding to the first 21 amino acids of the N-terminal tail of histone H3. In the presence of horseradish peroxidase, H2O2 reacts with ADHP to produce the highly fluorescent compound resorufin that can be analyzed with an excitation wavelength between 530-540 nm and an emission wavelength between 585-595 nm.
Abcam 1,10-Phenanthroline, Metalloprotease inhibitor, 25G
MW 180.2 Da, Purity >99%. Membrane permeable chelating agent. Metalloprotease inhibitor. Chelates intracellular heavy metals including zinc, copper and iron. Binds DNA and modulates multiple signaling pathways in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Batimastat (BB-94), Matrix metalloprotease (MMP) inhibitor
Potent, broad-spectrum MMP inhibitor
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC MG-132 25mg 1211877-36-9
MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 ?M and 1.2 ?M for the inhibition of proteasome and calpain, respectively. MG132 activates autophagy and induces apoptosis in tumor cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Benzonase endonuclease | 9025-65-4 | MFCD00131010 | 5 mil units
Benzonase endonuclease | 9025-65-4 | MFCD00131010 | 5 mil units
Abcam Serine Protease Assay Kit (FAM-Leu-DAP), 100 Tests
These Serine Protease Assay Kits enable researchers to detect intracellular chymotrypsin-like serine protease activity in vitro without lysing the cell.
The product is subject to the following: Abcam Restricted Use Statement