PIK-75 HCl is a p110? inhibitor with IC50 of 5.8 nM (200-fold more potently than p110?), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays. *For Research & Development use only. Product is not intended for drug, household, or human consumption.