Biochemical Reagents, Bafilomycin A1, Vacuolar H ATPase inhibitor, CAS 88899-55-2, 95% by TLC/NMR (Conforms), Macrolide antibiotic derived from Streptomyces griseus that is a potent and selective inhibitor of vacuolar H-ATPases (IC50 0.6 – 1.5 nM).1,2 Inhibits autophagy via disruption of fusion between autophagosomes and lysosomes.3