Protein Purification
Bioworld CHAPS, 5 g
A nondenaturing Zwitterionic detergent suitable for use as a solubilizing agent for membrane proteins due to the disruption of non-specific protein interactions. Ref: Hjelmeland, L.H., Proc. Nat. Acad. Sci. USA, 77, 6368 (1980) Specifications:Ultra Pure GradeConductivity (10%, Water): <=50umhosResidue on Ignition: <=0.1%Purity (TLC): One spot method, >99.9%.Appearance: SolidDensity : 1.01 g/cm3 at 20 °CMelting Point: 157 °C (dec.)
Selleck Chemical LLC BMS-777607 50mg 1025720-94-8
BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM in cell-free assays, 40-fold more selective for Met-related targets versus Lck, VEGFR-2, and TrkA/B, and more than 500-fold greater selectivity versus all other receptor and non receptor kinases. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
AdipoGen Leupeptin Hemisulfate, 103476-89-7, MFCD00037012, 100 mg
MF: C20H38N6O4 . 0.5 H2SO4, MW: 426.6 . 49.0, ≥97%, Appearance: White to off-white powder. Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. Shown to inhibit activation-induced programmed cell death. Antioxidant and anti-inflammatory agent. Widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest.
ACROBiosystems Human 4-1BB Ligand 2.5mg
ActiveMax Human 4-1BB Ligand / TNFSF9 (71-254) uBeads premium grade (for cells) are uniform superparamagnetic beads of 5.5 µm with streptavidin on its surface and coupled with biotinylated Human 4-1BB Ligand / TNFSF9 (71-254) Protein expressed from human 293 cells (HEK293) and contains AA Arg 71 - Glu 254 (Accession # P41273-1 ).
Cayman Chemical mP-2mP-9 InhIbItr IIItr 1mg
An inhibitor of MMP-2 and MMP-9 (IC50s = 10-20 μM, for both); selective for MMP-2 and MMP-9 over MT1-MMP, MMP-8, and MMP-13 as well as the serine proteases trypsin-2, neutrophil elastase, and cathepsin G (500 μM); reduces migration of HT1080 fibrosarcoma, C8161 melanoma, SKOV3 ovarian carcinoma, and KS1767 Kaposi's sarcoma cells in vitro; pretreatment delays tumor formation in an MDA-MB-435 mouse xenograft model; prevents growth of established tumors in MDA-MB-435 and KS1767 mouse xenograft models
Biochain Institute Inc Membrane Protein - Human Adult Normal Tissue: Small Intestine: Duodenum, 0.1 mg/PK
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
ATHENA ES Cyclodextrin Kit
Cyclodextrins’ unique molecular structure greatly promotes protein refolding. Cyclodextrins can suppress protein aggregation, protect against degradation and loss of protein function. They also bind well to detergents (aggregation suppressors), which allows for easy separation of the detergent from the protein, encouraging proper refolding. Differentcyclodextrins act and respond differently to different protein structures. Because of this, AthenaESTM provides 3 of the most common cyclodextrins in a simple screening kit so that the ideal conditions for refolding a given protein can be found quickly and easily. The Cyclodextrin Screening Kit can be particularly useful when paired with the Detergent Screening Kit. Individual cyclodextrins are also available for purchase.
Cayman Chemical S-NItroso-L-glutathIon 100mg
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.{1277,5064,4274,3632}
Hampton Research HR2-943-06/StockOptions MES #06 pH 5.7, 185 ml
HR2-943-06/StockOptions MES #06 pH 5.7, 185 ml. Please note items from this supplier are non-returnable.
Biochain Institute Inc Membrane Protein - Human Tumor Tissue: Testis, 0.1 mg/PK
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
Biochain Institute Inc Membrane Protein - Human Adult Normal Tissue: Brain: Pituitary, 0.1 mg/PK
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
Selleck Chemical LLC Pictilisib (GDC-0941) 50mg 957054-30-7 RG7321
Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3K?/? with IC50 of 3 nM in cell-free assays, with modest selectivity against p110? (11-fold) and p110? (25-fold). Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
ATHENA ES Refolding Buffer 1 - 500 ml
The QuickFoldTM Protein Refolding Kit is a screening kit that enables researchers to pinpoint the critical factors for refolding their protein in as little as 1 hour. Unlike many traditional kits, the Quick-FoldTM Kit employs a fractional factorial matrix design that allows the researcher to screen a specific protein in 15 different buffers quickly and easily. Researchers are able to examine a wider range of conditions all in a single experiment, simplifying the process of identifying the best buffer composition and method for the refolding of a given protein. The QuickFoldTM Kit comes with enough buffer for 10 refolding experiments, as well as supplemental Dithiothreitol and a Glutathione Redox System. Each buffer is available for individual purchase and is supplemented with the necessary Glutathione Redox System and/or DTT. Individual Buffers come in 500mL and 1L amounts.