MF: C24H33ClN4O6, MW: 508.99, Solubility: 313 mg/mL in DMSO, 50.5 mg/mL in EtOH with ultrasonic,insoluble in H2O. VX-765, an orally- absorbed pro-drug of VRT-043198, is a potent and selective inhibitor of caspase-1 which belongs to the ICE/caspase-1 sub-family caspases.