Protease Inhibitors and Phosphatase Inhibitors

Cayman Chemical MyelopRoxIdase InhIbItr Scr

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A state-dependent sodium channel inhibitor selectively binds to inactivated Nav channels over resting Nav channels (Kis 0.6 and 15 UM respectively) inhibits INa in primary rat acutely dissociated hippocampal neurons at 1 UM inhibits early- and late-phase nociceptive responses in the formalin test in mice (ED50s 10.6 and 5.2 mg/kg respectively) reduces the number of MES-induced tonic seizures in mice and rats

StemRD ALK-5 INHIBITOR 2 MG

Chemicals, ALK-5 Inhibitor, ALK-5 inhibitor, 2 mg

Cayman Chemical Erlotinib, 183321-74-6, 250 mg

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Molecular Formula C22H23N3O4, Purity ≥98%, Formula Weight 393.4, Synonyms: NSC 718781; A tyrosine kinase inhibitor which inhibits EGFR-associated kinase activity (IC50 = 2.5 M) and tumor growth in human HN5 tumor xenografts in mice with an ED50 value of 9 mg/kg; suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 M) and JAK2 mutant JAK2V617F positive hematopoietic progenitor cells (IC50 = 5 M).