Cell Line Lysates
Cayman Chemical MIcrococcIn P1 2.5mg
A macrocyclic peptide antibiotic that prevents the growth of Gram-positive bacteria without affecting that of Gram-negative bacteria
Biotium Primary Antibody Beta catenin Catenin Beta PAb CF740 1/EA
Beta-catenin associates with the cytoplasmic portion of E-cadherin The catenin/cadherin complexes play an important role mediating cellular adhesion including adherens junctions Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways and is also found in complexes with many different proteins including the tumor suppressor protein APC Defects in beta-catenin are associated with colorectal cancer as well as many other cancer types Beta-catenin is normally localized to the cell membrane but can translocate to the nucleus in response to certain cell signaling Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
ABclonal Technology Bcl10 Rabbit pAb
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
Biochain Institute Inc Total Protein - Parkinson's Disease: Brain: Occipital Lobe, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
ABclonal Technology ARRB2 Rabbit pAb
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Sigma Aldrich Fine Chemicals Biosciences HeLa Nuclear Extract
Nuclear extract prepared from human HeLa cells using a modified protocol of Dignam et al. which contains a variety of DNA binding proteins and transcription factors.
Abcam Human COL4A3BP (CERT) knockout HEK-293T cell lysate.
Human COL4A3BP (CERT) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology NeuN Rabbit pAb
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Cayman Chemical AquastatIn A 2.5mg
A fungal metabolite; active against S. aureus (MIC = 32 UG/ml); inhibits S. aureus fatty acid synthesis (IC50 = 3.5 µM); inhibits S. aureus Fabl (IC50 = 3.2 µM); inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 µM, respectively), as well as PTP1B (IC50 = 0.19 µM)
ABclonal Technology EML4 Rabbit pAb
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Biochain Institute Inc Total Protein - Multiple Sclerosis Disease: Brain: Precentral Gyrus, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
Cayman Chemical Myca uba bak Myctn 100mg
A flavonoid with diverse biological activities; active against B. subtilis, E. coli, K. pneumoniae, S. aureus, and C. albicans (MIC = 0.25 mg/ml for all); inhibits AChE and α-glucosidase in vitro (IC50s = 65 and 79 μg/ml, respectively); inhibits LPS-induced production of TNF-α and enhances LPS-induced RANTES production in RAW 264.7 cells at 0.2 and 1 mM
Cayman Chemical A-54556B 2.5mg
A natural acyldepsipeptide that is effective against Gram-positive bacteria, including penicillin-resistant S. aureus; is also effective against many strains of anaerobic bacteria
Abcam Human TIMM17B knockout HEK-293T cell lysate.
Human TIMM17B knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology EMC8 Rabbit pAb
Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytosol. Part of EMC complex.