Cell Line Lysates
Cayman Chemical 4-hydroxy Valsartn 2.5mg
A major metabolite of valsartan; reduces epinephrine and collagen-induced platelet aggregation in human whole blood
Cayman Chemical THUNDERHumn IL18 TRFRET 96
A sandwich TR-FRET immunoassay for the quantitative measurement of human IL‑18 (IL-1F4) in cell culture supernatants
Abcam Human IDH3G knockout HEK-293T cell lysate.
Human IDH3G knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical PolygodIal pyrIdazIn 2.5mg
A derivative of polygodial; inhibits the growth of MCF-7 and Hs 683 cells (GI50s = 72 and 93 μM, respectively)
ABclonal Technology NFAT2 Rabbit pAb
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Cayman Chemical 3OAcetyl2deoxycytIdIn 2.5mg
An acetylated derivative of 2'-deoxycytidine-5'-triphosphate
ABclonal Technology CD26/DPP4 Rabbit pAb
The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19.
Cayman Chemical PalmarumycIn C3 2.5mg
A fungal metabolite; active against A. tumefaciens, B. subtilis, P. lachrymans, R. solanacearum, S. haemolyticus, and X. vesicatoria (MICs = 6.25, 6.25, 12.5, 12.5, 6.25, and 6.25 UG/ml, respectively); active against M. microspora, E. repens, F. oxysporum, and U. violacea in agar diffusion assays at 0.5 mg/disc; scavenges DPPH radicals in cell-free assays and has antioxidant activity in a β-carotene-linoleic acid bleaching assay (IC50s = 37.57 and 7.41 UG/ml, respectively)
ABclonal Technology RbAp46/RBBP7 Rabbit pAb
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Cayman Chemical PenIcolInate B 2.5mg
A fungal metabolite with diverse biological activities; active against M. tuberculosis (MIC = 25 UG/ml), as well as P. falciparum, B. cereus, and C. albicans (IC50s = 1.4, 25, and 3.67 UG/ml, respectively); cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 6.21, 17.78, 0.307, and 2.79 UG/ml, respectively)
Cayman Chemical 6-hydroxy Dexamethason 2.5mg
An active metabolite of dexamethasone; reduces cortisol production in rats at 1 mg/kg
Cayman Chemical Humn LIver X ReceptrBeta 96Wel
LXRβ Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments.[INDIGO Catalog Nos. IB00301-32, IB00301, IB00302]