Cell Line Lysates
Cayman Chemical Mutnt IDH1-IN-1 10mg
An inhibitor of mutant IDH1 (IC50s = 42, 4, and 80 nM for IDH1R132H/R132H, IDH1R132C/R132C, and IDH1R132H/WT, respectively, for conversion of α-KG to 2-HG); selective for IDH1 mutant conversion of α-KG to 2-HT over IDH1WT/WT conversion of isocitrate to α-KG (IC50 = 1,998 nM) and over IDH2 (IC50s = >10,000 nM); inhibits 2-HG production in vitro (IC50 = 81.5 nM)
Cayman Chemical ThIelavIn B 2.5mg
A fungal metabolite that inhibits cyclooxygenase, blocking both the conversion of AA to PGH2 and the conversion of PGH2 to PGE2 (IC50s = 40 and 9 µM, respectively); also inhibits the reverse transcriptase of avian myeloblastosis virus, bacterial transglycosylases, and telomerase activity
Cayman Chemical KIbdelon B 2.5mg
A kibdelone whose mode of action and pharmacology have not been studied
Cayman Chemical S 5AdenosylLmethIonIn 2.5mg
A ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases
Cayman Chemical Humn GlucocortIcoId RECPTR 384
Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments.[INDIGO Catalog Nos. IB00201-32, IB00201, IB00202]
Cayman Chemical TrIchostatIn C 2.5mg
A glycosylated derivative of trichostatin A that has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A
Sino Biological Recombinant Human CNR1 Protein (VLP, Flag-Strep & His tag)
A DNA sequence encoding the Human CNR1 (P21554-1) (Met1-Ser414) was expressed, with a Flag tag followed by a Strep Tag at the N-terminus, a polyhistidine tag at the C-terminus. This protein was prepared using our VLP platform.As an innovative technology platform, VLPs are generated through the self-assembly of viral proteins in HEK293 cells. This process efficiently integrates membrane proteins onto the VLP surface, preserving their native conformation and yielding soluble, high-concentration proteins that are ideally suited for immunization and antibody screening.
Sino Biological Human MUC-1 Protein (aa890-1158, His Tag), Biotinylated
A DNA sequence encoding the Human MUC1 (P15941-1) (Ser890-Gly1158) was expressed with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro.
World Precision Instrument Liquid Waveguide Capillary Cell, 50 cm pathlength
UV/VIS/NIR absorbance spectroscopy is governed by Beer’s Law, where the absorbance signal is proportional to chemical concentration, light path length and the compound’s specific molar absorption coefficient. Typical optical pathlengths of cuvettes and flow cells are between 0.2cm and 10 cm. Longer pathlengths are difficult to achieve due to mechanical constraints. Liquid Waveguide Capillary Cells (LWCCs) fill this gap. LWCCs are fiber optic flow cells that combine an increased optical pathlength (10–500 cm) with small sample volumes ranging from 2.4 µL to about 3mL. Compared with a standard 1cm cell, a 1 mAU signal is enhanced one hundred fold with a 100 cm flowcell to 100 mAU, using WPI’s patented aqueous waveguide technology.*
They can be connected via optical fibers to a spectrophotometer with fiber optic capabilities.
Sino Biological Recombinant Human CD98 Protein (FITC conjugated, His Tag)
A DNA sequence encoding the Human SLC3A2 (P08195) (Arg206-Ala630) was expressed, with a polyhistidine tag at the N-terminus.
Cayman Chemical OlIgomycIn D 2.5mg
A macrolide antibiotic that inhibits the mitochondrial F1FOATPase; inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cyctoxic to SW620 colon cancer cells with an IC50 value of 36 µM
Cayman Chemical Humn LIver X ReceptrBeta 96Wel
LXRβ Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments.[INDIGO Catalog Nos. IB00301-32, IB00301, IB00302]
Abcam HeLa whole cell lysate
HeLa whole cell lysate
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical E6 BerbamIn 10mg
A calmodulin inhibitor that disrupts the activity of calmodulin-dependent enzymes such as myosin light chain kinase (IC50 = 8 µM) and phosphodiesterase 1A (IC50 = 0.53 µM); inhibits P-glycoprotein activity in purified primary cultured rat brain microvessel endothelial cells at 10 µM
ATCC Cervical Epithelial Cell Growth Kit
Cervical Epithelial Cell Growth Kit contains components that when added to Cervical Epithelial Cell Basal Medium (ATCC PCS-480-032) create a complete ATCC Primary Cell Solutions culture environment for cervical epithelial cells derived from normal human cervical tissue (eg, Primary Cervical Epithelial Cells, Normal, Human, ATCC PCS-480-011). The serum-free medium supports normal cervical cell morphology, promote rapid growth, and proliferation. No feeder layers, extracellular matrix proteins, or other substrates are required.