Cell Line Lysates
Cayman Chemical 7hydroxy CLOrpromazInhyd 2.5mg
An active metabolite of chlorpromazine; increases plasma prolactin levels in male rats at 5 mg/kg; reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats at 1.6 mg/kg
ABclonal Technology ARRB2 Rabbit pAb
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Sino Biological Recombinant Human TRPM7 Protein (GST Tag), Active
Recombinant human CHAK1 (TRPM7) (1158-1865) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Cayman Chemical PsoromIc AcId 2.5mg
An inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 µM) and P. falciparum FAS-II; cytotoxic to U87MG and KB cancerous cell lines (IC50s = 79.40 and 56.22 mg/L, respectively); active against Plasmodium species (IC50 = 29.2 µM against blood stage P. falciparum)
ABclonal Technology ASS1 Rabbit mAb
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
Cayman Chemical Scopulaops F244 ymglusn 2.5mg
A fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme; targets cell walls of pathogens such as S. aureus in a mouse sepsis model of infection
Abcam LYPD2 overexpression 293T lysate (whole cell).
LYPD2 overexpression 293T lysate (whole cell).
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology EEA1 Rabbit pAb
Enables 1-phosphatidylinositol binding activity, GTP-dependent protein binding activity, and protein homodimerization activity. Involved in endocytosis, vesicle fusion, and viral RNA genome replication. Located in cytosol and early endosome. Is extrinsic component of plasma membrane.
ABclonal Technology CNPase Rabbit pAb
Predicted to enable 2,3-cyclic-nucleotide 3-phosphodiesterase activity. Involved in substantia nigra development. Located in several cellular components, including extracellular space, microtubule, and plasma membrane. Implicated in hypomyelinating leukodystrophy 20, multiple sclerosis, and schizophrenia. Biomarker of alcoholic liver cirrhosis, multiple sclerosis, and restless legs syndrome.
ABclonal Technology Human Parkin Rabbit pAb
The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Cayman Chemical MST-AS5568 L-681 217 2.5mg
An antibiotic; active against Gram positive and Gram negative bacteria at 255 UG/ml; inhibits bacterial protein synthesis (EC50 = 0.4 µM in E. coli); increases EF-Tu-associated GTPase activity (EC50 = 6 µM in E. coli)
Cayman Chemical Bak BH372-87humntrIf 10mg
A Bak-derived peptide; selectively binds to Bcl-xL over Bcl-2 (EC50s = 174 and 3,020 nM, respectively); induces apoptosis in LLC-PK1 cells
ABclonal Technology EML4 Rabbit pAb
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
ABclonal Technology MYL9 Rabbit mAb
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.