Tissue Lysates
Cell Sciences Inc Elranatamab Research Grade BiTE Antibody, Bispecific T-Cell Engager, High Purity >99%, 1 mg
Elranatamab is a research-grade bispecific monoclonal antibody that targets BCMA and CD3, enabling T-cell-mediated destruction of myeloma cells. It offers >99% purity, making it ideal for high-quality research in oncology and immunology. This liquid formulation is stable, requires storage at -20°C for 12 months, and ships with dry ice, ensuring integrity for sensitive experiments.
Cayman Chemical SynthetIc OmbuIn 1mg
A flavonoid with diverse biological activities; an antagonist of M1 mAChRs (Ki = 42 µM in CHO-K1 cells expressing the human receptor); cytotoxic to HepG2 cancer cells (IC50 = 1.5 UG/ml); reduces blood urea and glucose levels, urinary volume and protein levels, serum creatinine levels, renal fibrosis levels, and body weight in a rat model of STZ-induced diabetic nephropathy at 40 mg/kg per day
Cayman Chemical PalmItIc AcId13CC2 labeled 1mg
An internal standard for the quantification of palmitic acid by GC- or LC-MS
Cayman Chemical CCK27-33non-sulfated 1mg
A C-terminal fragment of CCK; inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 µM); inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 µM)
Cayman Chemical SynthetIc PInosylvIn 1mg
A stilbene with diverse biological activities; activates SIRT1 and induces glucose uptake in isolated rat L6 skeletal muscle myotubes; reduces radial growth in a panel of 28 plant pathogenic fungi at 100 μg/ml; reduces expression of MMP-2, MMP-9, and membrane type 1-MMP in and inhibits migration of HT-1080 cells; reduces the number of tumor nodules and lung tumor weight in a CT26 mouse xenograft model of metastatic colon cancer at 10 mg/kg; decreases hind paw volume and MPO activity in a rat model of adjuvant-induced arthritis; exhibits plant antifeedant activity against L. americanus
Cayman Chemical SynthetIc DIeugenol 1mg
A neolignan with antioxidative and antiprotozoal activities; inhibits TBARS formation and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays; has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s = 15.1 and 11.5 µM, respectively) but is cytotoxic to NCTC L-929 fibroblasts (CC50 = 58.2 µM); disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce ROS production in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages
Cayman Chemical BacopasIde I 1mg
A saponin with diverse biological activities; inhibits MAO-A and MAO-B (IC50s = 17.08 and 94.22 UG/ml, respectively); decreases immobility time in the tail suspension and forced swim tests, as well as brain MDA levels, and increases brain SOD and GPX activities in mice at 5, 15, and 50 mg/kg; increases time spent in the target quadrant in the Morris water maze and reduces amyloid plaque formation in the APP/PS1 transgenic mouse model of Alzheimer’s disease; reduces cerebral edema and infarct volume in a rat model of transient focal ischemia induced by middle cerebral artery occlusion at 3, 10, and 30 mg/kg
Cayman Chemical SynthetIc NImbIn 1mg
A limonoid with diverse biological activities; inhibits the growth of D. oryzae by 64.8% at 1,000 ppm; has antifeedant activity against S. littoralis in a choice test at 0.02-2,000 μM; decreases melanin content to 20.9% of control in B16 murine melanoma cells at 25 μg/ml; inhibits TPA-induced activation of EBV-EA in Raji cells (IC50 = 499 mol ratio/32 pmol TPA)
Cayman Chemical SynthetIc ErysolIn 1mg
An isothiocyanate with anticancer activity; inhibits the proliferation of MCF-7, HeLa, A549, HepG2, and SW480 cells (IC50s = 1.62, 1.12, 5.22, 14, and 8.14 µM, respectively); enhances arsenic trioxide-induced apoptosis and cytotoxicity in HL-60, U937, and K562 cells at 3 µM
Cayman Chemical 1 3-DInonadecnoyl Glycerol 1mg
A diacylglycerol; has been used as a standard in the quantification of diacylglycerols in synthetic milk fat by SPE/HPLC/ELSD
Cayman Chemical SynthetIc AlysIn 1mg
An isothiocyanate with diverse biological activities; active against a variety of bacteria; directly inhibits PAH-induced CYP1A1 and CYP1A2 activity in MCF-7 cells at 0.5-2.5 µM; inhibits proliferation of HCT116 colon cancer cells (IC50 = 50s = 168 and 20 µM, respectively)
Cayman Chemical CardIolIpIn18 018 018 01 1mg
A phospholipid containing the long-chain saturated fatty acid stearic acid
Cayman Chemical SynthetIc XAV939 1mg
A small molecule inhibitor of tankyrase 1 and 2 (IC50 = 11 and 4 nM, respectively); increases the protein levels of the axin-GSK3β complex and promotes the degradation of β-catenin; inhibits colony formation of APC-deficient colorectal cancer cells at 0.33 µM