Tissue Lysates
Cayman Chemical SynthetIc OmbuIn 1mg
A flavonoid with diverse biological activities; an antagonist of M1 mAChRs (Ki = 42 µM in CHO-K1 cells expressing the human receptor); cytotoxic to HepG2 cancer cells (IC50 = 1.5 UG/ml); reduces blood urea and glucose levels, urinary volume and protein levels, serum creatinine levels, renal fibrosis levels, and body weight in a rat model of STZ-induced diabetic nephropathy at 40 mg/kg per day
Cayman Chemical SynthetIc DIeugenol 1mg
A neolignan with antioxidative and antiprotozoal activities; inhibits TBARS formation and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays; has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s = 15.1 and 11.5 µM, respectively) but is cytotoxic to NCTC L-929 fibroblasts (CC50 = 58.2 µM); disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce ROS production in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages
Cayman Chemical BacopasIde I 1mg
A saponin with diverse biological activities; inhibits MAO-A and MAO-B (IC50s = 17.08 and 94.22 UG/ml, respectively); decreases immobility time in the tail suspension and forced swim tests, as well as brain MDA levels, and increases brain SOD and GPX activities in mice at 5, 15, and 50 mg/kg; increases time spent in the target quadrant in the Morris water maze and reduces amyloid plaque formation in the APP/PS1 transgenic mouse model of Alzheimer’s disease; reduces cerebral edema and infarct volume in a rat model of transient focal ischemia induced by middle cerebral artery occlusion at 3, 10, and 30 mg/kg
Cell Biologics GFP-Expressing Monkey Primary Kidney Glomerular Endothelial Cells
GFP-Expressing Monkey Primary Kidney Glomerular Endothelial Cells
Cell Biologics RFP-Expressing Monkey Primary Kidney Fibroblasts
RFP-Expressing Monkey Primary Kidney Fibroblasts
Cell Biologics B129 Mouse Primary Kidney Glomerular Endothelial Cells
B129 Mouse Primary Kidney Glomerular Endothelial Cells