Cayman Chemical SynthetIc OmbuIn 1mg
A flavonoid with diverse biological activities; an antagonist of M1 mAChRs (Ki = 42 µM in CHO-K1 cells expressing the human receptor); cytotoxic to HepG2 cancer cells (IC50 = 1.5 UG/ml); reduces blood urea and glucose levels, urinary volume and protein levels, serum creatinine levels, renal fibrosis levels, and body weight in a rat model of STZ-induced diabetic nephropathy at 40 mg/kg per day