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A sterol-derived hormone that acts as a ligand of DAF-12 (EC50 = 23 nM; 50 nM, inhibits the dauer-promoting activity of DAF-12, blocking the formation of infective larvae in several parasitic nematodes in favor of reproductive maturation to adults
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A benzylisoquinoline alkaloid with diverse biological activities; selectively binds to the dopamine D1 and D2 receptors (Kis = 22 and 214 nM, respectively) over 5-HT1A and 5-HT2A receptor subtypes in HEK293 cells at 10 µM; inhibits proliferation in a panel of leukemia cell lines (IC50s = 2.7-6.5 µM); inhibits methamphetamine-induced conditioned place preference in mice at 5 mg/kg
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A flavone with diverse biological activities; scavenges ABTS radicals in a cell-free assay (IC50 = 0.312 mg/ml); reduces virus titer and expression of IE1 and UL54 in HCMV-infected HEL cells from 0.1-10 µM; inhibits IgE-induced degranulation of RBL-2H3 cells (IC50 = 4.83 µM); reduces tumor growth and the number of lung metastases in a CT26 murine colon carcinoma model at 37.5 mg/kg per day
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A peptide hormone; binds to ferroportin, inducing its internalization and degradation, which increases intracellular iron levels and decreases dietary iron absorption and plasma iron levels; bactericidal against multidrug-resistant clinical isolates of Gram-negative and Gram-positive bacteria from 6.25-50 UG/ml; levels are increased in the serum of patients with CKD
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More