Tissue Lysates
Cayman Chemical SynthetIc Curzeren 1mg
A sesquiterpene with diverse biological activities; scavenges DPPH radicals in a cell-free assay at 3.36 UG/L with a synergistic effect when used in combination with eucalyptol; active against F. graminearum at 0.5 mg/ml; inhibits the proliferation of SK-MEL-19 melanoma cells (IC50 = 5.17 UG/ml), as well as AGP-01 gastric and HCT116 colon cancer cells (IC50s = 8.04 and 9.18 UG/ml, respectively) and MRC-5 non-cancerous human fibroblasts (IC50 = 11.45 UG/ml); induces apoptosis in, and decreases migration of, SK-MEL-19 cells at 5 and 10 µM; reduces tumor weight in an SPC-A1 mouse xenograft model at 135 mg/kg
Cayman Chemical 2ArachIdonyl Glycerold5 100ug
An internal standard for the quantification of 2-AG by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Gecko2 Human Whole Genome1EA
Developed by Feng Zhangs lab at the Broad Institute the human GeCKO v2 (all-in-one vector) libraries consist of over 100000 unique gRNAs for gene knock-out in the human genome. Using an all-in-one lenti CRISPR vector which co-expresses Cas9 gRNA with a puromycin selection marker the version 2 vector produces nearly 10X higher titer virus than version 1. The human single vector system GeCKO pool is provided in 8 x 25 ul aliquots at a minimum titer of 5X108 TU/ml (measured by a p24 assay). The GeCKO human library is delivered as two half-libraries (A and B). It is recommended to screen both A and B libraries together which will include 6 sgRNAs per gene (3 sgRNAs in each library). Both libraries contain 1000 non-targeting control sgRNAs. The A library also targets miRNAs (4 sgRNAs per miRNA).
