Clinical Chemistry Controls
Cayman Chemical 7-keto Cholesterol 50mg
A bioactive oxysterol; a major oxysterol component of oxidized LDL; produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by CYP7A1; inhibits CYP7A1 (IC50 = ~1 μM); induces activation and chemotaxis of retinal microglia as well as polarization to a pro-inflammatory state; increases ocular levels of VEGF, IL-1β, and GRO/KC, macrophage infiltration, and neovascularization in rat eye; levels are increased in lipid deposits in a variety of chronic diseases
ABclonal Technology Cystatin C Rabbit pAb
This gene encodes a type 2 cystatin, a cysteine protease inhibitor found in various human fluids and secretions, where it provides protective functions. It is the most abundant extracellular inhibitor of cysteine proteases, expressed in nearly all organs. The gene is located on chromosome 20, within the cystatin locus, which also contains genes and pseudogenes for other type 2 cystatins. A mutation in this gene is associated with amyloid angiopathy. Its expression is reduced in vascular smooth muscle cells in atherosclerotic and aneurysmal aortic lesions, indicating its role in vascular disease. The protein also has antimicrobial activity, inhibiting herpes simplex virus replication. Alternative splicing results in multiple transcript variants encoding the same protein.
DIAGNOSTICA STAGO INC Liatest D-Dimer
The STA - Liatest D-Di kit is an immuno-turbidimetric assay for the quantitative determination of D-dimer in venous plasma (in 3.2 % sodium citrate) for use on STA-R, STA Compact and STA Satellite analyzers by professional laboratory personnel.
ABclonal Technology Apolipoprotein CI Rabbit mAb
This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.