Clinical Chemistry Controls
Cayman Chemical 7-keto Cholesterol 100mg
A bioactive oxysterol; a major oxysterol component of oxidized LDL; produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by CYP7A1; inhibits CYP7A1 (IC50 = ~1 μM); induces activation and chemotaxis of retinal microglia as well as polarization to a pro-inflammatory state; increases ocular levels of VEGF, IL-1β, and GRO/KC, macrophage infiltration, and neovascularization in rat eye; levels are increased in lipid deposits in a variety of chronic diseases
Medchemexpress LLC Calreticulin/CALR M 250ug
Recombinant mouse calreticulin (CALR) with an N-terminal GST tag, supplied as 250 μg lyophilized material. The protein is a calcium-binding endoplasmic reticulum chaperone useful for biochemical characterization and antibody-binding assays; it is provided as a high-purity, stable preparation with recommended storage instructions.
ABclonal Technology Serotonin transporter Rabbit pAb
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodiumneurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.
Cayman Chemical 25-hydroxy Cholesterol 5mg
An oxysterol; suppresses endogenous cholesterol synthesis by binding INSIG proteins and preventing SREBPs from being transported to the Golgi; inhibits IgA class switching induced by LPS and various cytokines in B cells (IC50 = ~50 nM); inhibits replication of SARS-CoV-2 in Vero cells (EC50 = 3.675 µM) and reduces increases in viral protein production in infected Vero cells when used prior to infection; reduces viral RNA loads in the lung and trachea in a mouse model of SARS-CoV-2 infection at 100 mg/kg per day; serum levels are increased in patients with SARS-CoV-2.
![Biolegend FITC anti-mouse CD218a (IL-18Rα) [A17071D]; Isotype: Rat IgG2b κ; Reactivity: Mouse; Apps: FC; Size: 100 ug](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502557676.png-250.jpg)
Biolegend FITC anti-mouse CD218a (IL-18Rα) [A17071D]; Isotype: Rat IgG2b κ; Reactivity: Mouse; Apps: FC; Size: 100 ug
FITC anti-mouse CD218a (IL-18Rα) [A17071D]; Isotype: Rat IgG2b κ; Reactivity: Mouse; Apps: FC; Size: 100 ug