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Cayman Chemical SARSCoV2 nutralIzng ntIb 500uL
An NSAID and COX inhibitor (IC50s 7 and 4 UM for COX-1 and COX-2 respectively) reduces paw volume in a rat model of adjuvant-induced polyarthritis at 3 15 and 75 mg/kg induces antinociception in rats (ED50 54.3 mg/kg) reduces carrageenan-induced paw edema in rats at 20-180 mg/kg
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Cayman Chemical SARSCoV2 SpIke GlycoproteIn
A cGAS inhibitor (IC50 0.11 UM) inhibits dsDNA-induced IFN-B1-dependent gene expression in a reporter assay reduces basal Ifnb1 mRNA expression in BMDMs generated from the Trex1-/- mouse model of Aicardi-Goutières syndrome
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