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DSPE-PEG2000-iRGD is a lipid-PEG conjugate formed by linking distearoylphosphatidylethanolamine to the tumor-penetrating iRGD peptide (CRGDKGPDC) via a PEG2000 spacer. Supplied as a powder, it is intended for surface functionalization of liposomes and nanoparticles to confer tumor-homing and tumor-penetrating properties for targeted drug delivery studies.
Provides tumor-targeting via αv integrin binding.
Promotes tumor penetration through neuropilin-1 interaction after proteolytic cleavage.
Enables surface modification of liposomes and nanoparticles for targeted delivery.
Contains a PEG2000 spacer for steric stabilization and extended circulation.
Characterized by high purity and an average molecular weight for reproducible formulation.
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DMG-PEG2000-Biotin is a synthetic amphiphilic molecule composed of dimyristoyl glycerol (DMG) polyethylene glycol (PEG2000) and biotin functionalities It is commonly employed in biomedical research for surface modification of lipid-based delivery platforms such as lipid nanoparticles (LNPs) and liposomes The PEG moiety enhances colloidal stability prolongs circulation time and reduces rapid clearance in vivo The biotin termination facilitates conjugation to streptavidin-tagged biomolecules exploiting the highly specific biotin-streptavidin interaction Thus DMG-PEG2000-Biotin is valuable for drug-delivery optimization targeted therapeutic approaches and in vitro diagnostic assay development
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1 2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid used in the synthesis of liposomes and lipid nanoparticle (LNP) systems for research related to mRNA vaccines or drug delivery systems
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Total Lipid Extract is a chloroform:methanol extract of the respective tissue (Brain, Soybean, Heart, etc.). This extract is partitioned against deionized water, and the chloroform phase is concentrated.
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Molecular Formula C26H52NO7P, Purity >99% LPC; may contain up to 10% of the 2-LPC isomer, Formula Weight 521.667, Synonyms: 1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine
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18:1 Lyso PG is a high-purity, synthetic lysophospholipid detergent provided by Avanti Polar Lipids. This nonbilayer-forming lipid is crucial in membrane research due to its detergent-like properties, effectively disrupting membrane integrity. It plays a pivotal role as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) in phosphoglycerol synthesis and is frequently used as a lipid standard in liquid chromatography-mass spectrometry (LC-MS) method optimization.
High purity greater than 99%
Liquid physical form
Utilizes chloroform as solvent
Packaged in 5 x 4 mL ampules
Unit size of 500 mg
Concentration of 25 mg/mL
Requires shipping on dry ice
Stored at -20°C
Empirical formula: C24H46O9PNa
CAS number: 326495-24-3
Molecular weight of 532.58 g/mol
MDL number: MFCD00672604
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