Living Organisms
Cayman Chemical BIX01294 (hydrochloride hydrate), Purity: ≥98%, CAS: 1808255-64-2, 50 mg
A selective inhibitor of G9a histone methyltransferase (IC50 = 1.7 μM); less effectively inhibits G9a-like protein (GLP; IC50 = 38 μM) and has no effect on other known histone methyltransferases
Cayman Chemical Cefsulodin (sodium salt hydrate), Purity: ≥95%, CAS: 1426397-23-0, 500 mg
A cephalosporin antibiotic; active against 45 isolates of P. aeruginosa (MIC90 = 3.1 µg/ml) and acts synergistically against P. aeruginosa isolates when combined with gentamicin, tobramycin, amikacin, or mezlocillin; binds to P. aeruginosa PBP1a, PBP1b, and PBP3 but not PBP2, PBP4, or PBP5; increases survival in mice infected with various P. aeruginosa strains (ED50s = 1.93-137 mg/kg for all)
Cayman Chemical L-Tyrosine (sodium salt hydrate), Purity: ≥98%, 50 g
A conditionally essential amino acid; a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones; plasma, skeletal muscle, and erythrocyte levels are decreased in patients with chronic kidney disease
Cayman Chemical Doxapram (hydrochloride hydrate), Purity: ≥95%, CAS: 7081-53-0, 25 mg
A central respiratory stimulant; increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg; acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation
Cayman Chemical Doxapram (hydrochloride hydrate), Purity: ≥95%, CAS: 7081-53-0, 10 mg
A central respiratory stimulant; increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg; acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation
Enterprise Technology Solutions Learning Resources Garden Set,Hide/Seek,Veggies/Bunny,Multicolor
Hide and Seek Vegetable Garden lets children discover new counting, color and memory skills as they search for the funny bunny. As children search the pots for the hidden bunny, they will also use this preschool toy to strengthen their memory and critical-thinking skills. Each piece is made with recycled plastic as a sustainable way to learn, play and grow. Game also includes an activity guide filled with child-friendly sustainability facts and preschool learning activities that help children discover new ways to keep things green. Set includes five pots, four vegetables and one fun bunny. Learning toy is perfect for children ages 18 months and older.
Cayman Chemical Cefotiam (hydrochloride hydrate), Purity: ≥80%, 1 g
A broad-spectrum cephalosporin antibiotic; inhibits the growth of S. aureus (MIC50 = 0.26 µg/ml), as well as P. aeruginosa, E. coli, and H. influenzae (MIC50s = 1, 0.06, and 0.01 µg/ml, respectively); increases survival in mouse models of infection with strains of S. aureus (ED50s = 3.5 and 8.3 mg/kg) and E. coli (ED50s = 0.5-25 mg/kg)
Cayman Chemical Clodronate (sodium salt hydrate), Purity: ≥95%, CAS: 88416-50-6, 10 mg
A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC50 = 1.34 µM) and bone resorption; is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce apoptosis of macrophage-like cells and cancer cells
Cayman Chemical Harmalol (hydrochloride hydrate), Purity: ≥98%, CAS: 6028-00-8, 100 mg
A β-carboline alkaloid and an active metabolite of harmaline; an inhibitor of DYRK1A (IC50 = 0.63 µM); an inhibitor of MAO-A (IC50 = 0.66 µM); selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM; inhibits proliferation of H4 human glioblastoma cells (IC50s = 23.7 µM); reduces TCDD-induced increases in CYP1A1 levels in HepG2 cells and prevents TCDD-induced activation of AhR in guinea pig hepatic cytosolic extracts; reduces glutamate-induced cytotoxicity, cytochrome c release, caspase-3 activation, and ROS production in PC12 cells at 25 µM
Cell Biologics Cynomolgus Monkey Primary Small Intestinal Smooth Muscle Cells
Cynomolgus Monkey Primary Small Intestinal Smooth Muscle Cells
Cayman Chemical A-943931 (hydrochloride hydrate), Purity: ≥98%, 1 mg
A histamine H4 receptor antagonist (Ki = 3.8 nM); inhibits clobenpropit-induced scratching in mice (ED50 = 26 µmoles/kg, i.p.)
Cayman Chemical A-943931 (hydrochloride hydrate), Purity: ≥98%, 5 mg
A histamine H4 receptor antagonist (Ki = 3.8 nM); inhibits clobenpropit-induced scratching in mice (ED50 = 26 µmoles/kg, i.p.)