Living Organisms
Cayman Chemical FrovatrIptnsuccInAT hydra 50mg
An agonist of 5-HT1B and 5-HT1D receptors (Kis = 2.51 and 3.98 nM, respectively); selective for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2C, 5-HT3, and 5-HT7 receptors, as well as dopamine D1, D2, and D3, histamine H1, and α1-adrenergic receptors (Kis = >50 nM); induces contractions in human basilar arteries isolated post-mortem, coronary arteries from transplant recipient hearts, and coronary arteries from donor hearts unsuitable for transplantation (EC50s = 13.8, 41.69, and 15.49 nM, respectively); increases carotid vascular resistance in closed-chest and open-chest anesthetized dogs (ED50s = 6 and 1 nmol/kg, i.v., respectively)
Cayman Chemical DoxapramhydroCLOrID hydra 10mg
A central respiratory stimulant; increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg; acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation
Cayman Chemical CefsulodInsodIum salt hydra 1g
A cephalosporin antibiotic; active against 45 isolates of P. aeruginosa (MIC90 = 3.1 UG/ml) and acts synergistically against P. aeruginosa isolates when combined with gentamicin, tobramycin, amikacin, or mezlocillin; binds to P. aeruginosa PBP1a, PBP1b, and PBP3 but not PBP2, PBP4, or PBP5; increases survival in mice infected with various P. aeruginosa strains (ED50s = 1.93-137 mg/kg for all)
MicroQuant™ Bacillus spizizenii, high CFU (ATCC 6633-HQ-PACK™)
MicroQuant™ Bacillus spizizenii (high CFU) is a quantitated, best-in-class control. This ISO 17034 reference material is provided as a pack containing 5 vials of cryopreserved pellets (107 to 108 CFU per vial) and 5 vials of rehydration buffer. This convenient, single-use format rehydrates immediately and is easy to use and stored at 2–8°C. The strain is recommended for use in compendial testing and is not intended for therapeutic or diagnostic applications.
Biosafety Level: BSL-1
Additional recommended strains for high quantitated MicroQuant™ formats:
E. coli (NC3456067, ATCC 8739-HQ-PACK™)
P. paraeruginosa (NC3456054, ATCC 9027-HQ-PACK™)
S. aureus subsp. aureus (NC3456070, ATCC 6538-HQ-PACK™)
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MicroQuant™ Escherichia coli, low CFU (ATCC 8739-LQ-PACK™)
MicroQuant™ Escherichia coli (low CFU) is a quantitated, best-in-class control. This ISO 17034 reference material is provided as a pack containing 5 vials of cryopreserved pellets (100 to 1,000 CFU per vial) and 5 vials of rehydration buffer. This convenient, single-use format rehydrates immediately and is easy to use and stored at 2–8°C. The strain is recommended for use in compendial testing and is not intended for therapeutic or diagnostic applications.
Biosafety Level: BSL-1
Additional recommended strains for USP <62>:
C. albicans (NC3456089, ATCC 10231-LQ-PACK™)
S. aureus subsp. aureus (NC3456072, ATCC 6538-LQ-PACK™)
P. paraeruginosa (NC3456065, ATCC 9027-LQ-PACK™)
C. sporogenes (TBD, ATCC 19404-LQ-PACK™)
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MicroQuant™ Bacillus spizizenii, low CFU (ATCC 6633-LQ-PACK™)
MicroQuant™ Bacillus spizizenii (low CFU) is a quantitated, best-in-class control developed to support USP General Chapter <61>. This ISO 17034 reference material is provided as a pack containing 5 vials of cryopreserved pellets (100 to 1,000 CFU per vial) and 5 vials of rehydration buffer. This convenient, single-use format rehydrates immediately and is easy to use and stored at 2–8°C. The strain is recommended for use in compendial testing.
Biosafety Level: BSL-1
Additional recommended strains for USP <61>:
P. paraeruginosa (NC3456065, ATCC 9027-LQ-PACK™)
S. aureus subsp. aureus (NC3456072, ATCC 6538-LQ-PACK™)
C. albicans (NC3456089, ATCC 10231-LQ-PACK™)
A. brasiliensis (NC3456088, ATCC 16404-LQ-PACK™)
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FOCUS BIOMOLECULES Biochemical Reagents, Domoic acid, Marine natural product neurotoxin, CAS 14277-97-5, 98% by HPLC/NMR (Conforms)
Biochemical Reagents, Domoic acid, Marine natural product neurotoxin, CAS 14277-97-5, 98% by HPLC/NMR (Conforms), Kainic acid-type neurotoxin produced by certain species of the marine pennate diatom Pseudo-nitzschia, is responsible for amnesic shellfish poisoning.1 Suspension feeders such as bivalve mollusks can accumulate and retain high amounts of DA in their tissues, threatening human health.2,3 DA is a potent agonist at kainate and AMPA receptors4 and induces convulsive behavior and seizures in rodents5. It induces structural and molecular changes in the developing zebra fish nervous system.6
Cayman Chemical CefsulodInsodIM salt hydra
A cephalosporin antibiotic; active against 45 isolates of P. aeruginosa (MIC90 = 3.1 UG/ml) and acts synergistically against P. aeruginosa isolates when combined with gentamicin, tobramycin, amikacin, or mezlocillin; binds to P. aeruginosa PBP1a, PBP1b, and PBP3 but not PBP2, PBP4, or PBP5; increases survival in mice infected with various P. aeruginosa strains (ED50s = 1.93-137 mg/kg for all)