Resins and Supports
Bachem Fmoc-Suberol
Fmoc-Suberol, 5-Fmoc-amino-2-carboxymethoxy-10,11-dihydro-5H-dibenzo[a,d]cycloheptene, 212783-75-0, C32H27NO5, Mr 505.57, 25g. Ramage Linker. A linker suitable for Fmoc-SPPS of peptide amides. Cleavage is achieved e.g. with 95% TFA, scavengers may be required.
eMolecules 431041-83-7 | RINK AMIDE MBHA RESIN (100-200 MESH, 1% DVB, 0.3-0.8MMOL/G) | AstaTech732.877 | C47H44N2O6 | 95.000 | COc1ccc(C(NC(=O)OCC2c3ccccc3-c3ccccc23)c2ccc(OCC(=O)NC(c3ccc(C)cc3)c3ccc(C)cc3)cc2)c(OC)c1 | 25g | 784435626
RINK AMIDE MBHA RESIN (100-200 MESH, 1% DVB, 0.3-0.8MMOL/G) | AstaTech | 431041-83-7732.877 | C47H44N2O6 | 95.000 | COc1ccc(C(NC(=O)OCC2c3ccccc3-c3ccccc23)c2ccc(OCC(=O)NC(c3ccc(C)cc3)c3ccc(C)cc3)cc2)c(OC)c1 | 25g | 784435626
Bachem 2-Methoxy-4-alkoxybenzyl alcohol resin
SASRINTM resin (100-200 mesh, 0.7-1.0 mmol/g), 2-Methoxy-4-alkoxybenzyl alcohol resin, 124760-64-1, 5g. 3-CH3O-4-HOCH2-Ph-O-CH2-Ph-polymer.
Chem-Impex International, Inc. L-Valine-2-chlorotrityl resin (0.3 - 0.8 meq/g, 200 - 400 mesh) | MFCD06809947 | 1G
L-Valine-2-chlorotrityl resin (0.3 - 0.8 meq/g, 200 - 400 mesh), MFCD06809947, 1G
Apexbio Technology LLC DMAP 1122-58-3 25g
4-Dimethylaminopyridine (DMAP) (CAS 1122-58-3) is a pyridine-based aromatic amine commonly utilized as a nucleophilic catalyst DMAP exerts its catalytic activity through nucleophilic activation transiently coordinating to acyl intermediates to facilitate efficient acyl transfer reactions Based on these properties DMAP holds research potential in the synthetic modification of peptides nucleotides and bioactive molecules drug synthesis derivatization of natural compounds and the preparation of bioactive molecular scaffolds for therapeutic development
Bachem H-Asp(OtBu)-2-chlorotrityl resin (200-400 mesh, 0.50-0.90 mmol/g)
H-Asp(OtBu)-2-chlorotrityl resin (200-400 mesh, 0.50-0.90 mmol/g), 1g.
Bachem 4-ALKOXYBENZYL ALCOHOL R/ 25G
Wang resin#4-Benzyloxybenzyl alcohol resin#4-HOCH₂-Ph-O-CH₂-Ph-polymer. 25g. MFCD00131778. The Wang support, p-benzyloxybenzyl alcohol resin, is the most widely used resin for attaching carboxylic acids for further functionalization. Cleavage conditions for the ester anchor involve concentrated TFA or TFA/CH₂Cl₂ to provide carboxylic acids or cyclization-cleavage under acidic or basic conditions. Release of an amide function by treatment with an amine in the presence of a Lewis acid was also reported. Wang resin was used to add vinyl and iodobenzoic acids via carbodiimide coupling and the products subjected to Heck conditions with alkenes or with alkynes or to Suzuki coupling with boron reagents. The Ugi multicomponent condensation reaction was conducted on Wang resin with the carboxylic acid, amine or isonitrile as the anchored functional group.
Chem-Impex International, Inc. TentaGel HL NH2 (0.3 - 0.8 meq/g, 100 - 200 mesh) | MFCD00217899 | 5G
TentaGel HL NH2 (0.3 - 0.8 meq/g, 100 - 200 mesh), MFCD00217899, 5G
Chem-Impex International, Inc. TentaGel S NH2 (0.2 - 0.8 meq/g, 130 µm) | MFCD00217899 | 5G
TentaGel S NH2 (0.2 - 0.8 meq/g, 130 µm), MFCD00217899, 5G