Isotopically Labeled Compounds
Cayman Chemical StearIc AcId-d5 5mg
An internal standard for the quantification of stearic acid by GC- or LC-MS
Medchemexpress LLC Trametinib-d4 | 871700-17-3 | 99.9% | 619.42 | 25 MG
Trametinib-d4 is the deuterium-labeled version of Trametinib. Trametinib is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of approximately 2 nM. It also activates autophagy and induces apoptosis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium substitution has the potential to impact the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC L-Xylose-2-13C | 478506-63-7 | 99.0% | C₄¹³CH₁₀O₅ | 25 MG
L-Xylose-2-13C is the 13C labeled L-Xylose. L-Xylose is a rare sugar and the levorotatory form of Xylose. It can be utilized as a raw material for the synthesis of various drugs and bioactive molecules. Stable heavy isotopes of elements such as hydrogen and carbon have been integrated into drug molecules for use as tracers for quantitation during the drug development process.
- Serves as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical 2-NonylquInolIn-4 1H-on-d4 5mg
An internal standard for the quantification of 2-nonylquinolin-4(1H)-one by GC- or LC-MS
Cayman Chemical 13 S-HODE-d4 100ug
An internal standard for the quantification of 13-HODE by GC- or LC-MS
Medchemexpress LLC L-Methionine-DL-sulfoximine (MSX; MSO) | 15985-39-4 | MFCD00002621 | 98.0% | 1 ML
L-Methionine-DL-sulfoximine (MSX; MSO) is a highly specific and irreversible inhibitor of Glutamine synthetase (GS). It is also a potent convulsant that primarily affects astroglia metabolically and morphologically. This product is for research use only.
- Inhibits Gln-dependent ammonia-stimulated neuronal toxicity in vitro
- Potentiates Gln deficit-dependent depression
- Significantly increases fixed nitrogen release in cyanobacteria
- Promising candidate for research in biofertilizers
- Promising candidate for research in convulsive seizures
Medchemexpress LLC Adipic acid-d8 | 52089-65-3 | 99.7% | 154.19 g/mol | C6H2D8O4 | 100 MG
Adipic acid-d8 is the deuterium-labeled form of adipic (hexanedioic) acid supplied as a high-purity isotopic standard for analytical and research applications. It is used as an internal standard, tracer, or calibration reference in mass spectrometry, NMR, and method development.
- Deuterium-labeled (d8) for clear mass shifts in MS analyses.
- High purity suitable for use as an analytical reference material.
- Compact 100 mg quantity convenient for laboratory workflows.
- Known molecular weight and formula for accurate calculations.
- Suitable for quantitative LC-MS/MS, GC-MS, and NMR applications.
Medchemexpress LLC Terconazole-d4 | 1398065-50-3 | 5 MG
Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication used for the treatment of vaginal yeast infection.
- Deuterium labeled compound
- Broad-spectrum antifungal
- Treats vaginal yeast infection
Medchemexpress LLC Lyso-platelet-activating factor C-16-d4 | 201216-37-7 | 99.0% | C24H48D4NO6P | 100 UG
Lyso-PAF C-16-d4 is the deuterium labeled Lyso-PAF C-16. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for quantitation during drug development processes, with the potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Prucalopride-13C,d3 | 2140306-00-7 | 99.0% | C1713CH23D3CIN3O3 | 1 MG
Prucalopride-13C,d3 is the 13C- and deuterium labeled Prucalopride, used largely as a tracer for quantitation during drug development. Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs. This product has not been fully validated for medical applications and is for research use only.
- Stable heavy isotopes incorporated into drug molecules
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- Target: 5-HT receptor
- Pathway: GPCR/G protein; neuronal signaling
Medchemexpress LLC L-Valine-13C5,15N | 202407-30-5 | 123.10 | 5 MG
L-Valine-13C5,15N is a 13C- and 15N-labeled L-Valine, a nonlinear semiorganic material. It causes lipid peroxidation, accumulates malondialdehyde (MDA), and inhibits cyanobacteria. It also inhibits multidrug-resistant bacteria by activating the PI3K/Akt pathway and inhibiting arginase. This compound serves as a tracer and an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS, utilizing stable heavy isotopes for drug development and pharmacokinetic studies.
- 13C- and 15N-labeled L-Valine
- Inhibits cyanobacteria and multidrug-resistant bacteria
- Functions as a tracer
- Acts as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Utilizes stable heavy isotopes for drug development and pharmacokinetic studies
Medchemexpress LLC 7-keto-deoxycholic acid | 911-40-0 | MFCD00271373 | 99.5% | 406.56 | C24H38O5 | 10 MG
7-keto-Deoxycholic acid (Standard) is an analytical reference standard of the bile acid metabolite 7-keto-deoxycholic acid for research and analytical applications, including method development, HPLC, and mass spectrometry. It is supplied as a high-purity solid with documented solubility and defined storage conditions.
- Analytical standard for metabolite identification and quantification.
- High purity suitable for analytical workflows (assay and HPLC measurements reported).
- Molecular formula C24H38O5 and molecular weight 406.56 provide exact mass reference.
- Available in small solid packages and solution formats for flexible use.
- Soluble in DMSO (requires sonication) and formulatable into in vivo vehicle preparations achieving ≥ 2.5 mg/mL.
- Store solid protected from light at 4°C; store solutions frozen (-80°C for long term, -20°C short term).
Cayman Chemical EtIfoxIn-13C-d3 1mg
An internal standard for the quantification of etifoxine by GC- or LC-MS
Cambridge Isotope Laboratories CHLOROACETIC ACID (D3, 98%), 5 G, 1796-85-6
CHLOROACETIC ACID (D3, 98%), 5 G, 1796-85-6
