Isotopically Labeled Compounds
Medchemexpress LLC Yohimbine-d3 | 133146-00-6 | 99.36% | 10 MG
Yohimbine-d3 is the deuterium labeled Yohimbine. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Impacts pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Mebeverine acid-d5 hydrochloride | 475203-77-1 | 99.0% | 10 MG
Mebeverine acid-d5 hydrochloride is a deuterium-labeled form of Mebeverine acid hydrochloride, a secondary metabolite of the intestinal antispasmodic agent Mebeverine. This metabolite is formed in the body through hydrolysis and serves as a key circulating marker for oral Mebeverine.
- Deuterium-labeled compound
- Secondary metabolite of mebeverine
- Key circulating metabolite for oral mebeverine
- Used as a tracer and internal standard
- Suitable for quantitative analysis methods
- Purity of 99.0%
Medchemexpress LLC Selexipag-d7 | 1265295-21-3 | 98.4% | 503.66 | 1 MG
Selexipag-d7 is the deuterium-labeled Selexipag, an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor). Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for use as tracers in drug development, with potential to affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
Medchemexpress LLC Pimozide-d4 | 1803193-57-8 | 99.2% | 1 MG
Pimozide-d4 is a deuterium labeled Pimozide. It acts as a dopamine receptor antagonist with Ki values of 1.4 nM, 2.5 nM, and 588 nM for dopamine D2, D3, and D1 receptors, respectively. It also has an affinity at α1-adrenoceptor with a Ki of 39 nM, and inhibits STAT3 and STAT5. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled compound
- Dopamine receptor antagonist (D2, D3, D1)
- Affinity at α1-adrenoceptor
- Inhibits STAT3 and STAT5
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Alpha-D-glucose-13C | 287100-64-5 | 99.4% | 100 MG
Alpha-D-glucose-13C is a 13C labeled alpha-D-glucose, which is an endogenous metabolite. It is intended for research use only, not for medical applications.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes as tracers for quantitation during drug development
Medchemexpress LLC Tempone-15N,d16 (4-oxo-Tempo-15N,d16) | 80404-14-4 | 1 MG
Tempone-15N,d16 is the deuterium and 15N labeled Tempone, serving as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium and 15N labeled compound
- Solid appearance, light yellow to yellow color
- Soluble in DMSO (requires ultrasonic and warming)
Medchemexpress LLC Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) | 2272886-41-4 | 99.2% | 565.71 | 1 MG
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline that can be used as the internal standard for the analysis of Omadacycline. This product is for research use only.
- Deuterium labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 16:0-18:1 PG-d5 | 1246298-34-9 | 98.0% | 771.07 | 1 MG
16:0-18:1 PG-d5 is deuterium labeled 16:0-18:1 PG. It is for research use only and not sold to patients. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC CER10-d9 | 2260669-52-9 | 99.0% | 548.97 | 1 MG
CER10-d9 is a deuterium-labeled version of CER10, designed for research purposes. It is explicitly stated that it is not for sale to patients. This compound is offered in solid form and presents as a white to off-white substance.
- Tracer application
- Internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS
- Deuterium labeling incorporates stable heavy isotopes of hydrogen
- Availability in multiple quantities
- Quality boasts a purity of 99.0%
Medchemexpress LLC Fingolimod-d4 | 1346747-38-3 | MFCD19704989 | 99.1% | 311.50 | 100 MG
Fingolimod-d4 is the deuterium labeled Fingolimod. It is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist and also functions as a pak1 activator and an immunosuppressant. Deuterium labeling allows its use as a tracer for quantitation during drug development and has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled
- Brain-penetrant sphingosine 1-phosphate (S1P) antagonist
- Pak1 activator
- Immunosuppressant
- Can be used as tracers for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Retinoic acid-d5 | 78996-15-3 | 99.07% | 305.47 | 1 MG
Retinoic acid-d5 is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid binds to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ozenoxacin-d3 (hydrochloride) | 245765-41-7 | ≥99.0% | 402.89 | 5 MG
Ozenoxacin-d3 hydrochloride is a deuterium-labeled form of Ozenoxacin hydrochloride. Ozenoxacin hydrochloride is a nonfluorinated quinolone antibacterial that exhibits potent activities against the main microorganisms isolated from skin and soft tissue infections. This compound can be utilized as a tracer or as an internal standard for quantitative analysis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Exhibits potent activities against microorganisms isolated from skin and soft tissue infections
Medchemexpress LLC Tecovirimat-d4 | 869572-92-9 | 98.95% | 380.35 | 5 MG
Tecovirimat-d4 is a deuterium-labelled Tecovirimat (HY-14805), an orally bioavailable and selective compound effective against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox, and variola viruses. It targets the orthopoxvirus protein VP37, which is essential for membrane envelopment of intracellular mature virus particles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Azilsartan-d5 (TAK-536-d5) | 1346599-45-8 | 99.4% | 461.48 | 1 ML
Azilsartan-d5 is the deuterium-labeled Azilsartan (TAK-536), a specific and potent angiotensin II type 1 receptor antagonist. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled Azilsartan
- Specific and potent angiotensin II type 1 receptor antagonist
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS