Isotopically Labeled Compounds
Medchemexpress LLC 4,4'-((Pentane-1,5-diyl-1,1,5,5-d4)bis(oxy))dibenzimidamide dihydrochloride | 1276197-32-0 | 98.0% | 1 MG
Pentamidine-d4 dihydrochloride is the deuterium labeled Pentamidine dihydrochloride. It is an antimicrobial agent that interferes with DNA biosynthetics. This product appears as a white to off-white solid with a purity of 98.0% and an isotopic enrichment of 99.2%.
- Deuterium labeled compound
- Antimicrobial agent
- Interferes with DNA biosynthetics
- White to off-white solid
- Purity 98.0%
- Isotopic enrichment 99.2%
- Recommended storage at 4°C, sealed, away from moisture
- Recommended storage in solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Rifampicin-d3 | 1262052-36-7 | 95.7% | 1 MG
Rifampicin-d3 is a deuterium labeled form of Rifampicin, a potent and broad-spectrum antibiotic. It exhibits activity against bacterial pathogens and anti-influenza virus activities. This compound is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules for quantitation
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Acetylcholine-d9 chloride | 344298-95-9 | 99.0% | 1 MG
Acetylcholine-d9 chloride is a deuterium-labeled acetylcholine chloride, which is a potent, BBB-permeable cholinergic agonist. This neurotransmitter modulates the activity of dopaminergic neurons by stimulating nicotinic acetylcholine receptors and inhibits p53 mutant peptide aggregation in vitro. It can be utilized as a tracer or an internal standard for quantitative analysis through techniques like NMR, GC-MS, or LC-MS.
- Deuterium-labeled acetylcholine chloride
- Potent and BBB-permeable cholinergic agonist
- Modulates dopaminergic neuron activity
- Inhibits p53 mutant peptide aggregation in vitro
- Suitable as a tracer or internal standard for quantitative analysis
Medchemexpress LLC Alectinib-d6 | 1616374-19-6 | 98.05% | 1 MG
Alectinib-d6 is deuterium labeled Alectinib, a potent, selective, and orally available ALK inhibitor. It effectively penetrates the central nervous system (CNS) and inhibits ALK F1174L and ALK R1275Q with high potency.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Alverine-d5 citrate | 1215327-00-6 | 98.5% | 1 MG
Alverine-d5 citrate is a deuterium-labeled analog of Alverine citrate, categorized as an isotope-labeled compound. It is a white to off-white solid with a purity of 98.5%. This compound can be used in research as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- White to off-white solid appearance
- Purity of 98.5%
- Utilized as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS techniques
- Molecular weight: 478.59
- Chemical formula: C26H30D5NO7
- Isotopic enrichment: 99.6%
- Storage as powder: 3 years at -20°C, 2 years at 4°C
- Storage in solvent: 6 months at -80°C, 1 month at -20°C
Medchemexpress LLC Pendimethalin-d5 | 1219803-39-0 | 99.9% | 1 MG
Pendimethalin-d5 is the deuterium labeled Pendimethalin. Pendimethalin is an herbicide that controls annual grasses and certain broadleaf weeds. It inhibits cell division and cell elongation.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-aspartic acid-13C4,15N | 202468-27-7 | MFCD00144566 | 98.0% | 138.07 | 13C4H7 15NO4 | 10 MG
L-Aspartic acid-13C4,15N is a stable isotope-labeled form of the amino acid L-aspartic acid used as a reference standard and tracer in analytical, metabolic, and mass spectrometry applications.
- Stable isotope-labeled (13C4, 15N) suitable as an internal standard for LC-MS/MS and quantitative assays.
- High purity; ≥98.0%.
- Molecular weight 138.07 provides consistent mass spectrometric behavior.
- Chemical formula 13C4H7 15NO4 reflects isotopic labeling.
- Supplied in small laboratory quantities for analytical workflows.
Medchemexpress LLC Ketotifen-d3 fumarate | 1795138-23-6 | 99.2% | 50 MG
Ketotifen-d3 (fumarate) is a deuterium-labeled version of Ketotifen fumarate. This compound is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, utilized for the prevention of asthma attacks.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sulfamethoxazole-13C6 | 1196157-90-0 | 99.9% | 1 MG
Sulfamethoxazole-13C6 is a 13C labeled Sulfamethoxazole (Ro 4-2130-13C6), which is a sulfonamide antibiotic with widespread antibacterial activity. It inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase.
- Suitable for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Probenecid-d14 | 1189657-87-1 | 99.5% | 1 MG
Probenecid-d14 is the deuterium labeled version of Probenecid. Probenecid is recognized as a potent and selective agonist for transient receptor potential vanilloid 2 (TRPV2) channels and has been observed to inhibit pannexin 1 channels. This compound is intended for research use only and can be utilized as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled version of Probenecid
- Potent and selective agonist for TRPV2 channels
- Inhibits pannexin 1 channels
- Can be used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis
- Molecular weight: 299.45
- Chemical formula: C13H5D14NO4S
- Appearance: Solid
- Color: White to off-white
- For research use only
Medchemexpress LLC Ketoprofen-13C,d3 | 1189508-77-7 | 1 MG
Ketoprofen-13C,d3 is the 13C- and deuterium labeled Ketoprofen. Ketoprofen is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Desloratadine-d5 | 1020719-34-9 | >99.7% | 1 MG
Desloratadine-d5 is a deuterium-labeled version of Desloratadine, an orally active major metabolite of the nonsedating H1-antihistamine Loratadine. It functions as a selective H1-receptor antagonist with anti-allergic and anti-inflammatory activities.
- Used as a tracer for quantitative analysis
- Acts as a selective H1-receptor antagonist
- Possesses anti-allergic and anti-inflammatory properties
- Can serve as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes for drug development and quantitation
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Nifedipine-d6 (BAY-a-1040-d6) | 1188266-14-9 | 1 MG
Nifedipine-d6 (BAY-a-1040-d6) is a deuterium labeled nifedipine, which acts as a potent calcium channel blocker. It is intended for research use only. Deuteration, the incorporation of stable heavy isotopes of hydrogen into drug molecules, has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Metronidazole-d3 | 83413-09-6 | MFCD27702816 | 100.0% | 1 MG
Metronidazole-d3 is a deuterium-labeled form of Metronidazole. It can be used for research purposes, including as a tracer or an internal standard for quantitative analysis by techniques like NMR, GC-MS, or LC-MS. This compound typically appears as a light yellow to yellow solid.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes incorporated into drug molecules.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sulfamethoxazole-d4 | 1020719-86-1 | 99.3% | 1 ML
Sulfamethoxazole-d4 is a deuterium-labeled sulfonamide antibiotic, also known as Ro 4-2130-d4. It demonstrates widespread antibacterial activity by inhibiting bacterial folate metabolism, specifically by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. This product is intended for research use only.
- Deuterium labeled analog
- Sulfonamide antibiotic with widespread antibacterial activity
- Inhibits bacterial folate metabolism
- Suitable for studying urinary tract infections (UTIs), prostatitis, and bronchitis
- Supplied as a 10 mM solution in DMSO