
Karl Fischer Buffers and Reagents
Buffers and reagents intended for use with Karl Fischer (KF) titration techniques. KF titration is a classic titration method that uses coulometric or volumetric titration to determine the moisture content of a sample.
Karl Fischer (KF) reagents are used in the analytical technique developed by chemist Karl Fischer to accurately measure the water content of gases, liquids, and solids.
Key applications include:
- Analyzing water content in raw materials and finished products
- Estimating moisture in food, pharmaceuticals, chemicals, and petroleum products
- Determining the water content of laboratory samples.
Karl Fischer reagents contain a variety of chemicals in proprietary formulations. Consult the SDS for individual products for appropriate handling instructions and precautions.
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Filtered Search Results

Titrant 5, MilliporeSigma™
Titrant 5 titrant for volumetric Karl Fischer titration with two component reagents H2O Aquastar™.
Buffer Solution for Strong Acids, ≤ 200 ppm, MilliporeSigma™
Buffer solution for strong acids for Karl Fischer Titration Aquastar™.
HYDRANAL™-Solvent CM, Medium for volumetric two-component Karl Fischer titration in non-polar substances, fats and oils (chloroform-methanol-based), Fluka, Honeywell
Molecular Formula: C3H4N2 Molecular Weight (g/mol): 68.08 MDL Number: MFCD00005183 InChI Key: RAXXELZNTBOGNW-UHFFFAOYSA-N IUPAC Name: 1H-imidazole SMILES: N1C=CN=C1
Molecular Weight (g/mol) | 68.08 |
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MDL Number | MFCD00005183 |
SMILES | N1C=CN=C1 |
IUPAC Name | 1H-imidazole |
InChI Key | RAXXELZNTBOGNW-UHFFFAOYSA-N |
Molecular Formula | C3H4N2 |
HYDRANAL™-Methanol Rapid, Medium for accelerated volumetric one-component Karl Fischer titration, Fluka, Honeywell
Molecular Formula: CH4O Molecular Weight (g/mol): 32.04 MDL Number: MFCD00004595 InChI Key: OKKJLVBELUTLKV-UHFFFAOYSA-N IUPAC Name: methanol SMILES: CO
Molecular Weight (g/mol) | 32.04 |
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MDL Number | MFCD00004595 |
SMILES | CO |
IUPAC Name | methanol |
InChI Key | OKKJLVBELUTLKV-UHFFFAOYSA-N |
Molecular Formula | CH4O |
HYDRA-POINT™ Karl Fischer Coulometric Vessel Solution, For Diaphragmless cell, Chloroform-Free, BAKER ANALYZED™ Reagent, J.T. Baker™
High quality chemicals for laboratory and specialized industrial use
Name Note | For Diaphragmless cell, Chloroform-Free |
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Packaging | Narrow Mouth Amber Glass Bottle |
Flash Point | 46.00°C |
Chemical Name or Material | HYDRA-POINT™ Karl Fischer Coulometric Vessel Solution |
Grade | BAKER ANALYZED™ Reagent |
HYDRA-POINT™ Solvent, Methanol-Free, BAKER ANALYZED™ Reagent, J.T. Baker™
High quality chemicals for laboratory and specialized industrial use
HYDRANAL™ - Solvent Oil, Reagent for volumetric two-component KF titration in oils (working medium), Honeywell Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
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Supports traceability with guaranteed access to certificates and proactive change notifications.
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Medium for volumetric two-component Karl Fischer titration in non-polar substances, fats and oils (methanol-hexanol-based)
CAS | 111-27-3 |
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MDL Number | MFCD00147197 |
Health Hazard 2 | P201-P210-P280-P308 + P311-P370 + P378-P403 + P235 |
HYDRANAL™ - Titrant 5 E, Reagent for volumetric two-component Karl Fischer titration (ethanol based), Honeywell™ Fluka™
Titrating agent for volumetric two-component Karl Fischer titration (ethanol-based)
UN Number | UN1170 |
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HYDRANAL™-Solver (Crude) oil, Honeywell Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More

Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More
Medium for volumetric one- and two-component Karl Fischer titration in oils (chloroform-methanol-xylene-based)
CAS | 288-32-4 |
---|---|
Health Hazard 2 | P201-P210-P280-P308 + P311-P370 + P378-P403 + P235 |
Flash Point | 6°C (42.8°F) |
UN Number | UN1992 |
Chemical Name or Material | HYDRANAL™-Solver (Crude) oil |
Density | 1.01g/mL |
Acetonitrile 50%, Water 47.5 % and Trifluoroacetic acid 2.5%, For mass spectrometry, Honeywell Riedel-de Haën™
Molecular Formula: C2H3N Molecular Weight (g/mol): 41.053 MDL Number: MFCD00001878 InChI Key: WEVYAHXRMPXWCK-UHFFFAOYSA-N PubChem CID: 6342 ChEBI: CHEBI:38472 IUPAC Name: acetonitrile SMILES: CC#N
PubChem CID | 6342 |
---|---|
Molecular Weight (g/mol) | 41.053 |
ChEBI | CHEBI:38472 |
MDL Number | MFCD00001878 |
SMILES | CC#N |
IUPAC Name | acetonitrile |
InChI Key | WEVYAHXRMPXWCK-UHFFFAOYSA-N |
Molecular Formula | C2H3N |
MilliporeSigma CombiTitrant 5 Keto
One component reagent for volumetric Karl Fischer titration for aldehydes and ketones