Native Proteins and Derivatives
ILEX LIFE SCIENCES LLC PORCINE THROMBIN PROTEIN 500 U
Ilex Life Sciences Thrombin Porcine, Purified Protein (500 U). DESCRIPTION: Thrombin Porcine, purified native enzyme, lyophilized. CAS REGISTRY NO.: 9002-04-4. FORMULATION: Sterile filtered white lyophilized (freeze-dried) powder. Lyophilized powder from glycine, calcium chloride pH 7.0 containing 0.9% NaCl. OTHER NAMES: Native thrombin protein, Porcine Activated Factor IIa, Factor 2A, F2, PT, RPRGL2, THPH1, coagulation factor II, EC 3.4.21.5, UniProtKB# P00735. APPLICATION: As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity.
American Research Products Inc Pig plasminogen actiVator inhi
Pig plasminogen actiVator inhibitor 1 PAI-1 ELISA Kit from CUSABIO Detection Range 0 312 ng/mL-20 ng/mL Sensitivity 0 078 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical GypenosIde IX 50mg
A dammarane-type triterpene saponin; prevents increases in iNOS, IL-6, and TNF-α levels, as well as phosphorylation of NF-κB, IκB, p38 MAPK, and Akt, induced by LPS and TNF-α in rat C6 glial at 25 μM; reduces LPS-induced increases in NF-κB, IκB, p38 MAPK, and Akt phosphorylation in mouse brain cortex at 30 mg/kg per day
Creative Diagnostics Bordetella pertussis Fimbriae 2/3, Fim 2 Subunit Molecular Weight 22,500 Da, Fim 3 Subunit Molecular Weight 22,000 Da, Antigen
The Bordetella pertussis Fimbriae 2/3 is an essential virulence factor that plays a major role in the adherence of Bordetella pertussis to the epithelial lining of the host respiratory tract. Comprising two distinct fimbriae serotypes (Fim 2 and Fim 3), these extracellular proteins are crucial for the attachment of the bacteria, thereby contributing to the infection process. This product is invaluable for research and development, particularly in the field of pertussis vaccine development.
- Critical for adherence to host epithelial cells
- Key for establishing Bordetella pertussis infection
- Valuable antigen for vaccine research
- Fimbriae serotypes: Fim 2 and Fim 3
- Fim 2 subunit molecular weight: 22,500 Da
- Fim 3 subunit molecular weight: 22,000 Da
- Subunits dissociate in SDS
- Antibodies to native Fim do not react well with SDS-denatured subunits
- Batch-dependent product
Cayman Chemical 2Deoxy3O Nmethylnthr 2.7mg
A fluorescent nucleotide derivative; decreases inositol phosphate formation in CHO-K1 cells expressing the human purinergic P2Y12 receptor at 100 µM; has been used to study the interaction between cardiac troponin I and myofibrils; ex/em = 356/453 nm, respectively
ABclonal Technology APOE Rabbit pAb
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Cayman Chemical ChymostatIn 50mg
A potent inhibitor of chymotrypsin and chymase (Ki = 9.36 and 13.1 nM, respectively), that less effectively blocks the activity of cathepsins, papain, and leukocyte elastase