Native Proteins and Derivatives
Cayman Chemical Sp2DeoxyadenosIn5O 1 2.1mg
An ETA receptor antagonist (Ki 13 nM in rat aortic vascular smooth muscle cells) inhibits ET-1-induced contractions in isolated rat aortic rings and mesenteric microvessels (pA2s 8.1 and 7.97 respectively) decreases systolic blood pressure in DOCA-salt hypertensive rats at 50 mg/kg decreases MAP and LVDP in normotensive pigs at 1 and 5 mg/kg reduces myocardial infarct size as a percentage of the area at risk in a porcine model of LAD coronary artery ligation-induced ischemia-reperfusion injury
Cayman Chemical 7Deaza2 deoxyadenosIn5 2.1mg
A diterpene with antileishmanial and gastroprotective activities induces mortality in L. donovani amastigotes (IC50 0.75 UM) reduces lesion area in a mouse model of hydrochloric acid and ethanol-induced gastric ulcers at 10 mg/kg
Abcam (R)-FSL-1, TLR2/6 agonist, 100UG
MW 1666.16 g/mol. Toll-like receptor 2/6 (TLR2/6) agonist. Synthetic lipoprotein. Represents N-terminal part of Mycoplasma salivarium LP44. NF-κB and MAPK pathway activator. Active in vivo. Rstereoisomer of FSL-1 (ab144863).
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Nat-20 S-yn 1mg
A positive allosteric modulator of 5-HT2A and 5-HT2C receptors selective for these receptors over a panel of 21 receptors and transporters at 10 UM enhances 5-HT-induced calcium release in CHO cells expressing recombinant human 5-HT2A or 5-HT2C at 1 nM reduces spontaneous locomotor activity in rats at 30 mg/kg
Cayman Chemical UDPsodIum salt 2.1mg
A metabolite of aripiprazole a potential impurity found in commercial preparations of aripiprazole
Abcam Z-Leu-Leu-CHO, Calpain inhibitor, 5MG
MW 362.5 Da, Purity >98%. Z-Leu-Leu-CHO, Calpain inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
BOVINE THROMBIN PROTEIN 2000 U
Ilex Life Sciences Thrombin Bovine, Purified Protein (2000 U). DESCRIPTION: Thrombin Bovine, purified native enzyme, lyophilized. CAS REGISTRY NO.: 9002-04-4. BIOLOGICAL ACTIVITY: 164 US units/mg protein (may vary with each lot number, please refer to enclosed datasheet). FORMULATION: Sterile filtered beige lyophilized powder; formulated with glycine, CaCl2 and sodium chloride, PH 6.8. APPLICATION: As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity. SYNONYMS: Activated Factor IIa, Factor 2A, F2, PT, RPRGL2, THPH1, coagulation factor II, EC 3.4.21.5, UniProtKB# P00735.
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Human & Mouse Phospho-RNA polymerase II (Ser2) Detection Kit, 50,000 Assay Points
AlphaLISA SureFire Ultra Human & Mouse Phospho-RNA polymerase II (Ser2) Detection Kit, 50,000 Assay Points
Abcam PD 151746, Calpain inhibitor, 5MG
MW 237.25 g/mol, Purity >96%. Cell permeable, selective, non-peptidic calpain inhibitor (Ki values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca²+ calpain sites. Shows antiapoptotic effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PD 151746, Calpain inhibitor, 25MG
MW 237.25 g/mol, Purity >96%. Cell permeable, selective, non-peptidic calpain inhibitor (Ki values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca²+ calpain sites. Shows antiapoptotic effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pheno x ybenzamine hydrochloride, calmodulin and alpha-adrenoceptor antagonist, 100MG
MW 340.3 Da, Purity >95%. Irreversible calmodulin antagonist (IC₅₀ ~ 80 μM) and potent, nonselective, irreversible α-adrenoceptor antagonist (IC₅₀ = 550 nM). Antihypertensive and anti-inflammatory effects in vitro and in vivo. Cell-permeable. Blood-brain barrier impermeable.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical SARSCoV2B 1 1 7Alpha Va 96
A PROTAC that drives androgen receptor degradation (DC50 <1 nM) inhibits tumor growth in various LNCaP and VCaP prostate cancer mouse xenograft models including an enzalutamide-insensitive non-castrated VCaP model
Cayman Chemical Dansyl Amde 5g
An internal standard for the quantification of prochlorperazine by GC- or LC-MS