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Lectins are carbohydrate-binding proteins omnipresent found in fungi plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in -strands and possesses a carbohydrate binding sites on the surface.
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A cholesterol ester; induces cytotoxicity in human monocyte-macrophages at 88-880 μM; levels are elevated 1.89-fold in the serum of pediatric patients with extrahepatic biliary atresia and decreased in the serum and plasma of patients with Alzheimer’s disease and abetalipoproteinemia, respectively, compared with healthy individuals
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A cholesterol ester that has been found in human meibum; can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals, but not patients with CESD or Wolman disease
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A cholesterol ester; a component of LDL; oxidiation of the arachidonate moiety contributes contributes to macrophage activation and foam cell formation in atherosclerosis; undergoes hydrolysis to release arachidonic acid during ACTH-stimulated prostaglandin synthesis in rat adrenocortical cells; levels increased in BLAF in pediatric cycstic fibrosis patients and placentas of women with chorioamnionitis
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