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Medchemexpress LLC 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate | 1416133-89-5 | MFCD22987956 | 99.9% | 462.39 g/mol | C21H20F6N2O3 | 25MG
SDP

Supplier:  Medchemexpress LLC HY1233225MG

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JW 642 is a potent, selective inhibitor of monoacylglycerol lipase (MAGL) intended for research use. It is supplied as a high-purity solid and is used in biochemical and pharmacological studies to probe MAGL activity in vitro and in vivo.

  • Potent MAGL inhibitor; IC50: mouse 7.6 nM, rat 14 nM, human 3.7 nM.
  • Selective over FAAH; FAAH IC50s: mouse 31 μM, rat 14 μM, human 20.6 μM.
  • Purity 99.90%.
  • Molecular formula C21H20F6N2O3; molecular weight 462.39 g/mol.
  • Appearance white to off-white solid.
  • Solubility DMSO ≥100 mg/mL; in vivo formulations achieve ≥2.5 mg/mL.
  • For research use only.

Catalog No. 50-002-35485


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