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Medchemexpress LLC 1,1,1-Trifluoroethyl-PEG2-azide | 1835759-68-6 | 97.0% | C6H10F3N3O2 | 100 MG
Supplier: Medchemexpress LLC HY140845100MG
1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with molecules that have DBCO or BCN groups.
- Used in the synthesis of PROTACs.
- Contains an Azide group, making it a click chemistry reagent.
- Can react with Alkyne groups via copper-catalyzed azide-alkyne cycloaddition.
- Can react with DBCO or BCN groups via strain-promoted alkyne-azide cycloaddition.
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