1,1-Dioxobenzo[b]thiophen-2-ylmethyl chloroformate, tech. 90%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
1,1-Dioxobenzo[b]thiophen-2-ylmethyl chloroformate is used for protection of amino acids as their benzothiophenesulfone-2-methoxycarbonyl (Bsmoc) derivatives, which represent a significant improvement in solid-phase peptide synthesis over the corresponding Fmoc derivatives.

Solubility
Reacts with water.

Notes
Store under inert gas. It is sensitive to moisture. Store in a cool, dry conditions in well sealed containers. Incompatible with oxidizing agents and bases.

Specifications

• CAS: 135204-19-2
• Molecular Formula: C10H7ClO4S
• Quantity: 1g
• MDL Number: MFCD01090984
• UN Number: UN3261
• Beilstein: 8258946
• Synonym: 1,1-dioxobenzo b thiophen-2-ylmethyl chloroformate, 1,1-dioxidobenzo b thiophen-2-yl methyl carbonochloridate, bsmoc-cl, acmc-20ap7q, 1-dioxobenzo b thiophen-2-ylmethyl chloroformate, benzo b thiophenesulfone-2-methoxycarbonyl chloride, 2-chlorocarbonyloxymethyl benzo b thiophene 1,1-dioxide, 1,1-dioxo-1-benzothiophen-2-yl methyl carbonochloridate, 1,1-dioxo-1??-benzothiophen-2-yl methyl carbonochloridate, 1,1-dioxo-1??-benzothiophen-2-yl methyl chloroformate
• InChI Key: ZYXGPSYADVTJGF-UHFFFAOYSA-N
• SMILES: ClC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O
• IUPAC Name: (1,1-dioxo-1λ⁶-benzothiophen-2-yl)methyl carbonochloridate
• Molecular Weight (g/mol): 258.67
• PubChem CID: 4565178
• Formula Weight: 258.68
• Percent Purity: 90%
• Grade: Technical
• Chemical Name or Material: 1,1-Dioxobenzo[b]thiophen-2-ylmethyl chloroformate

Safety and Handling

Hazard Category	Danger
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	GHS P Statement P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a Do not breathe dust/fume/gas/mist/vapors/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
Recommended Storage	2° to 8°C

SDS