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Medchemexpress LLC 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide | 1627138-52-6 | 99.9% | 494.53 g/mol | C23H25F3N4O3S | 10MG
SDP

Supplier:  Medchemexpress LLC HY1243910MG

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ML380 is a subtype-selective, brain-penetrant positive allosteric modulator of the M5 muscarinic acetylcholine receptor used in preclinical research to study M5 receptor pharmacology and central nervous system allosteric modulation. The compound is supplied as a high-purity solid and is available in small research-scale packages and solution formats for laboratory use.

  • Subtype-selective M5 mAChR positive allosteric modulator.
  • Brain-penetrant profile suitable for CNS studies.
  • Reported EC50 values: human M5 190 nM; rat M5 610 nM.
  • High purity appropriate for research applications.
  • Available in multiple small-scale solid and solution formats.
  • Storage recommendations provided for powder and in-solution stability.

Catalog No. 50-002-35808


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