1,2,2,6,6-Pentamethylpiperidine, 97%

Description

CAS: 79-55-0 | C10H21N | 155.285 g/mol

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.

Solubility
Soluble in toluene, dimethylformamide.

Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.

Specifications

Chemical Identifiers

• CAS: 79-55-0
• Molecular Formula: C10H21N
• Molecular Weight (g/mol): 155.285
• MDL Number: MFCD00006493
• InChI Key: XULIXFLCVXWHRF-UHFFFAOYSA-N
• Synonym: pempidine, pyrilene, perolysen, tenormal, piperidine, 1,2,2,6,6-pentamethyl, pempidina dcit, pempidine inn:ban, pempidinum inn-latin, unii-n5i18ji9d6, 1,2,2,6,6-pentamethyl-piperidine
• PubChem CID: 6603
• IUPAC Name: 1,2,2,6,6-pentamethylpiperidine
• SMILES: CC1(CCCC(N1C)(C)C)C

• Density: 0.858
• Boiling Point: 187°C to 188°C
• Flash Point: 50°C (122°F)
• Odor: Amine-like
• Quantity: 1 g
• UN Number: UN1992
• Beilstein: 103806
• Sensitivity: Air Sensitive
• Merck Index: 14,7080
• Solubility Information: Soluble in toluene,dimethylformamide.
• Formula Weight: 155.28
• Percent Purity: 97%
• Chemical Name or Material: 1,2,2,6,6-Pentamethylpiperidine

Safety and Handling

Hazard Category	H226-H301-H315-H319-H335
Hazard Statement	GHS H Statement H226-H302-H315-H319-H335 Flammable liquid and vapor. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S.
EINECSNumber	201-211-2
RTECSNumber	TN2190000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only