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Medchemexpress LLC 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide | 1638250-96-0 | MFCD29472267 | ≥95.0% | 391.4 | C19H17N7O3 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1898810MG

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ETC-159 is a potent, orally available porcupine (PORCN) inhibitor used in research to block Wnt ligand secretion and Wnt/β-catenin signaling. It inhibits β-catenin reporter activity with a reported IC50 of 2.9 nM and has been evaluated in preclinical and early clinical studies for Wnt-dependent cancers. Typical supplier purity is ≥95% and the compound is supplied as a crystalline solid.

  • Potent PORCN inhibition with low nanomolar activity.
  • Orally bioavailable for in vivo research applications.
  • Blocks Wnt ligand secretion and downstream β-catenin signaling.
  • Reported β-catenin reporter IC50 ~2.9 nM.
  • High purity (≥95%) and crystalline solid form.

Catalog No. 50-002-94652


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