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Cayman Chemical 1 2 3TrIoctnoyl GlycRol13 10mg
Supplier: Cayman Chemical 2946410 MG
A Smoothened receptor antagonist binds to human recombinant Smo expressed in HEK293T cells (IC50 1 1 UM) inhibits Gli1-mediated hedgehog signaling in a reporter assay (IC50 1 5 UM) an inhibitor of 11b-hydroxy steroid dehydrogenase-1 reduces tumor growth in a murine medulloblastoma mouse allograft model at 40 and 80 mg/kg per day) induces tumor regression at 80 mg/kg twice per day reduces expression of the hedgehog pathway-associated transcription factor Gli1 in tumor tissue
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