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Medchemexpress LLC 1-(2-(diethylamino)ethyl)-3-(2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl)thiourea | 688342-78-1 | 99.7% | 428.64 | C23H36N6S | 1MG
SDP

Supplier:  Medchemexpress LLC HY1246911MG

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D-I03 is a small-molecule selective RAD52 inhibitor used as a research reagent to study RAD52-dependent single-strand annealing and D-loop formation. It shows cellular activity against BRCA1- and BRCA2-deficient cells.

  • Selective RAD52 inhibitor with Kd 25.8 μM.
  • Inhibits RAD52-dependent single-strand annealing and D-loop formation.
  • Cellular activity: suppresses growth of BRCA1- and BRCA2-deficient cells.
  • Reported IC50 values: 5 μM (SSA) and 8 μM (D-loop).
  • Purity 99.7%.
  • Molecular weight 428.64 g/mol; formula C23H36N6S.
  • Physical state solid; color off-white to light yellow.
  • Solubility in DMSO 50 mg/mL.

Catalog No. 50-002-37171


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