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Medchemexpress LLC 1,2-dioleoyloxy-3-(dimethylamino)propane | 127512-29-2 | MFCD01321074 | >98.0% | C41H77NO4 | 10MG
Supplier: Medchemexpress LLC HY13075110MG
DODAP is an ionizable cationic lipid used to formulate liposomes and lipid nanoparticles for encapsulating and delivering nucleic acids such as siRNA and oligonucleotides. It is neutral at physiological pH and becomes protonated in acidic endosomal environments, aiding release of cargo and improving transfection efficiency.
- Ionizable cationic lipid for nucleic acid encapsulation
- pKa around 5.6 enabling endosomal protonation and cargo release
- High purity suitable for research applications (>98%)
- Compatible with common organic solvents for formulation work
- Used in liposome and LNP formulations to enhance delivery efficiency
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