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Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[PDP(polyethylene glycol)-2000] (ammonium salt) | 474922-24-2 | 90.0% | 2,987.79 g/mol | C140H273N4O55PS2 | 5 MG
Supplier: Medchemexpress LLC HY144000A5MG
DSPE-PEG2000-PDP is a PEGylated phospholipid bearing a pyridyldithio (PDP) functional group that enables thiol-reactive conjugation. It is used to introduce thiol-reactive handles into liposomes and lipid nanoparticles, providing PEG-based steric stabilization and a route for disulfide-mediated ligand attachment. Typical research applications include nanoparticle surface modification and targeted drug delivery.
- Enables thiol-reactive conjugation via pyridyldithio disulfide exchange.
- PEG2000 chain provides steric stabilization and reduced opsonization.
- Suitable for liposome and lipid nanoparticle surface modification.
- Allows attachment of thiol-containing ligands such as peptides or antibodies.
- Facilitates controlled surface density of functional groups.
- Available in small research pack sizes for formulation development.
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