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Cayman Chemical 1 2DI13 ZDocosenoyl3Ole 10mg

Supplier: Cayman Chemical 2716210 MG

An inhibitor of Skp2 inhibits the interaction between Skp2 and Skp1 to block Skp2 E3 ubiquitin ligase activity at 5 M inhibits Skp2 over Fbw7 andBTrCP E3 ubiquitin ligase activity in HEK293T cells reduces survival of LNCaP and PC3 prostate cancer cells via inhibition of aerobic glycolysis and induction of apoptosis reduces tumor volume in A549 lung cancer and PC3 prostate cancer mouse xenograft models at 40 and 80 mg/kg
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