Medchemexpress LLC 1(2H)-isoquinolinone, 5-hydroxy | 5154-02-9 | MFCD00006900 | 99.1% | 161.16 g/mol | C9H7NO2 | 10 MG

Supplier:  Medchemexpress LLC HYW01542210MG

1,5-Isoquinolinediol is a small-molecule PARP inhibitor used in research to modulate DNA repair and oxidative-stress pathways. It exhibits potent PARP inhibition and has been reported to reduce diabetes-induced NADPH oxidase-derived oxidative stress in retinal models. The compound is provided as a solid with high purity and is typically prepared in DMSO for in vitro and in vivo studies.

• Potent PARP inhibition (IC50 0.18-0.37 μM).
• Attenuates NADPH oxidase-derived oxidative stress in retinal models.
• High purity suitable for biochemical and cell-based assays.
• Soluble in DMSO (≈37 mg/mL) for convenient stock preparation.
• Stable as a powder when stored cold for extended periods.
• Applicable for studies of DNA repair, oxidative stress, and cell death pathways.

Catalog No. 50-003-03752