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Medchemexpress LLC 1-[3-(2,3-dichlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine | 2160546-07-4 | 100.0% | C17H18Cl2N6 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13709210MG

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IACS-13909 is a selective, potent, orally active allosteric inhibitor of SHP2 (PTPN11) used as a research compound to probe MAPK pathway signaling and antitumor activity in RTK-dependent models. It provides defined potency, high supplied purity, and solubility/formulation data to support in vitro and in vivo pharmacology studies.

  • Selective SHP2 allosteric inhibitor with IC50 15.7 nM and Kd 32 nM.
  • High supplied purity (99.97%) suitable for biological assays.
  • Soluble in DMSO at 10 mg/mL for in vitro use, with in vivo formulation options.
  • Available in multiple solid and solution pack sizes for flexible dosing.
  • Applicable to cellular and preclinical pharmacology studies of MAPK pathway signaling.

Catalog No. 50-002-61615


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