Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 25 MG

Supplier:  Medchemexpress LLC HY10406425MG

1A-116 is a small-molecule Rac1 inhibitor that selectively targets the W56 residue to prevent EGF-induced Rac1 activation and disrupt Rac1-P-Rex1 interaction. It induces apoptosis and inhibits cell proliferation, migration, and cell-cycle progression in a concentration-dependent manner, and has demonstrated antimetastatic activity in vivo. Molecular formula C16H16F3N3; molecular weight 307.31 g·mol⁻¹; reported purity 99.72%.

• Selective Rac1 inhibition via W56 targeting.
• Prevents EGF-induced Rac1 activation.
• Blocks Rac1-P-Rex1 interaction.
• Induces apoptosis and inhibits cell proliferation and migration.
• Demonstrates antimetastatic activity in vivo.

Catalog No. 50-002-41908