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Medchemexpress LLC 1,3-Butanedione, 4,4,4-trifluoro-1-(2-thienyl)- | 326-91-0 | MFCD00005445 | 99.9% | 25 G
Supplier: Medchemexpress LLC 25GHYD0190
2-Thenoyltrifluoroacetone is a chelating agent and a mitochondrial electron transfer chain inhibitor, demonstrating an IC50 value of 51.5 μM. It possesses the ability to chelate with various metal ions and exhibits both cytotoxicity and anti-tumor activity. The compound is anticipated to be significant in addressing diseases associated with mitochondrial dysfunction.
- Increases mitochondrial ROS production and induces microglial cell activation by inhibiting the mitochondrial electron transport chain.
- Exhibits cytotoxicity and anticancer activity on K562 cells by forming a complex with copper (II).
- Exhibits cytotoxicity and anti-tumor activity against MCF-7 and MKN-45 cells by forming a complex with zinc (II).
- Significantly inhibits carboxylesterase activity in rat plasma and mitochondria.
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