(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98%

Catalog No.	Quantity
AAA1888209	10 g
AAA1888218	50 g
AAA1888230	250 g

Catalog No. AAA1888209 Supplier Thermo Scientific Chemicals Supplier No. A1888209

Description

CAS: 52509-14-5 | C22H22BrO2P | 429.29 g/mol

It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II, for the preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands, in the synthesis and antitumor agents, in regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II, for the preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands, in the synthesis and antitumor agents, in regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization.

Solubility
Soluble in water (20°C).

Notes
Hygroscopic. Store away from water/moisture and oxidizing agents. Store under inert gas. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 52509-14-5
• Molecular Formula: C22H22BrO2P
• Molecular Weight (g/mol): 429.29
• MDL Number: MFCD00011966
• InChI Key: FRHRVQQUICVJDG-UHFFFAOYSA-M
• Synonym: 1,3-dioxolan-2-ylmethyl triphenylphosphonium bromide, 1,3-dioxolan-2-yl methyl triphenylphosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenylphosphanium bromide, phosphonium, 1,3-dioxolan-2-ylmethyl triphenyl-, bromide, 1,3-dioxolan-2-yl methyltriphenylphosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenyl phosphanium bromide, 1,3-dioxolan-2-ylmethyl triphenyl phosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenylphosphine, bromide, acmc-209kzy
• PubChem CID: 2724194
• IUPAC Name: 1,3-dioxolan-2-ylmethyl(triphenyl)phosphanium;bromide
• SMILES: [Br-].C(C1OCCO1)[P+](C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1

• Melting Point: 186°C to 189°C
• Quantity: 10 g
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water (20°C).
• Formula Weight: 429.3
• Percent Purity: 98%
• Chemical Name or Material: (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Safety and Handling

Hazard Category	H302+H312+H332-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	257-977-3
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only