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Medchemexpress LLC 1,3-disubstituted-7-aryl-5,5-bis(trifluoromethyl)-5,8-dihydropyrimido[4,5-d]pyrimidine-2,4-dione | 488097-06-9 | 99.7% | 440.73 g/mol | C16H11ClF6N4O2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY10111610MG

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GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS-penetrant, non-competitive small-molecule antagonist of the glucagon-like peptide 1 receptor (GLP-1R). It is intended for research use to block GLP-1R signaling in cellular and animal studies; reported potency (IC50) is 650 nM. Supplied as a high-purity solid or DMSO solution for experimental dosing and assay preparation.

  • Orally active and CNS-penetrant small molecule.
  • Non-competitive antagonist of GLP-1R with reported IC50 650 nM.
  • High reported purity suitable for research applications.
  • Available as solid or pre-made DMSO solution for convenience.
  • Suitable for in vitro and in vivo pharmacology studies.

Catalog No. 50-002-11264


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