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Cayman Chemical 1 3DIoctnoyl2Oleoyl Glyce 1mg
SDP

Supplier:  Cayman Chemical 268201 MG

Encompass_Preferred

An inhibitor of VEGFRs (IC50s 0.38 0.02 0.18 and 0.23 M for human VEGFR1 2 3 and mouse Vegfr2 respectively) selective for VEGFRs over FGFRs and PDGFRa (IC50s 10 M) but has activity at PDGFRB (IC50 1.4 M) in an enzyme assay inhibits VEGF-induced VEGFR2 autophosphorylation (IC50 11.5 nM in CHO cells transfected with the human receptor) blocks bFGF- and VEGF-induced angiogenesis (ED50s 9 and 26 mg/kg respectively) in a mouse model of growth factor-induced angiogenesis

Catalog No. 50-293-4741


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