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Cayman Chemical 1 3DIoleoyl2Stearoyl Glyce 5mg

Supplier: Cayman Chemical 268895 MG

A 5-HT1A receptor agonist (Ki 0.4 nM) selective for 5-HT1A over 5-HT1D 5-HT2 dopamine D1 and D2 and a1- and a2-adrenergic receptors (Kis 7.7 1000 1000 36 1000 and 1000 nM respectively) inhibits forskolin-stimulated cAMP synthesis in CHO cells transfected with human 5-HT1A induces hypothermia in mice (ED50 0.041 mg/kg) induces 5-HT syndrome as well as decreases accumulation of 5-HT and dopamine in rats (5 mg/kg) decreases arterial blood pressure and heart rate in a dose-dependent manner in spontaneously hypertensive rats reverses isolation-induced aggression in mice
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