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Medchemexpress LLC 1-[4-[5-chloro-4-(3,5-dimethyl-2-pyridinyl)-2-pyridinyl]piperazin-1-yl]-3-methylsulfonylpropan-1-one | 1373615-35-0 | MFCD22420827 | 99.3% | C20H25ClN4O3S | 10MG
SDP

Catalog No. 5000260062
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A potent, selective, orally active, and brain-penetrant Smoothened (Smo) antagonist for Hedgehog pathway research. The compound shows low-nanomolar affinity and inhibits Hh signaling in cellular and in vivo models, making it suitable for studies of tumor growth and brain metastasis driven by activated Hh signaling.

  • Potent Smo antagonist with low-nanomolar activity.
  • High selectivity for Smo versus related targets.
  • Orally active and brain penetrant in preclinical studies.
  • Useful for hedgehog pathway and tumor model research.
  • Supplied at high purity for experimental reproducibility.
  • Available in multiple small-scale pack sizes for research use.

Catalog No. 50-002-60062 Supplier Medchemexpress LLC Supplier No. HY1345910MG
May include imposed supplier surcharges.
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A potent, selective, orally active, and brain-penetrant Smoothened (Smo) antagonist for Hedgehog pathway research. The compound shows low-nanomolar affinity and inhibits Hh signaling in cellular and in vivo models, making it suitable for studies of tumor growth and brain metastasis driven by activated Hh signaling.

  • Potent Smo antagonist with low-nanomolar activity.
  • High selectivity for Smo versus related targets.
  • Orally active and brain penetrant in preclinical studies.
  • Useful for hedgehog pathway and tumor model research.
  • Supplied at high purity for experimental reproducibility.
  • Available in multiple small-scale pack sizes for research use.

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