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Medchemexpress LLC 1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]-4-fluoropiperidin-1-yl]propenone | 1415823-49-2 | 99.9% | C25H26FN5O2 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13948110MG

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TL-895 is a potent, orally active, ATP-competitive, irreversible Bruton's tyrosine kinase (BTK) inhibitor for research use. It exhibits low-nanomolar activity against recombinant BTK, inhibits BTK autophosphorylation, and reduces inflammatory cytokine production and cell migration in preclinical models, supporting its use in studies of B-cell malignancies and myelofibrosis.

  • Potent BTK inhibition at low-nanomolar concentrations.
  • Orally active compound suitable for in vivo studies.
  • Highly selective profile with limited off-target kinase activity.
  • Reduces production of inflammatory cytokines in cell assays.
  • Applicable for preclinical studies of B-cell malignancies and myelofibrosis.

Catalog No. 50-002-60117


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